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Can continuous glucose monitoring predict cystic fibrosis-related diabetes and ...
Zorron,Mariana; Marson,Fernando Augusto Lima; Morcillo,André Moreno; Gonçalves,Aline Cristina; El Beck,Mayra de Souza; Ribeiro,José DirceuABSTRACT Objective: To determine whether abnormal continuous glucose monitoring (CGM) readings (hypoglycemia/hyperglycemia) can predict the onset of cystic fibrosis-related diabetes (CFRD) and/or clinical impairment (decline in BMI and/or FEV1) in pediatric patients with cystic fibrosis (CF). Methods: This was a longitudinal prospective cohort study involving CF patients without diabetes at baseline. The mean f...
Are there differences in the physical activity level and functional capacity am...
Gianfrancesco,Lívea; Malheiro,Ana Paula Gaban; Matsunaga,Natasha Yumi; Oliveira,Marina Simões; Grotta,Milena Baptistella; Morcillo,André MorenoAbstract Objective The aim of this study was to analyze the physical activity level, using two tools, and the functional capacity of children and adolescents with asthma and with different levels of disease control, and to compare them to those of individuals without asthma. Methods Cross-sectional study with children and adolescents with (asthma group, AG) and without asthma (WAG), aged from 7 to 17 years. All...
Risk factors for recurrent wheezing in preterm infants who received prophylaxis...
Manini,Mariana Bueno; Matsunaga,Natasha Yumi; Gianfrancesco,Lívea; Oliveira,Marina Simões; Carvalho,Maria Rosa Vieira deABSTRACT Objective: To determine the prevalence of recurrent wheezing (RW) in preterm infants who received prophylaxis against severe infection with respiratory syncytial virus (RSV) and to identify genetic susceptibility (atopy or asthma) and risk factors for RW. Methods: This was a cross-sectional study involving preterm infants who received prophylaxis with palivizumab at a referral center in Brazil during t...
Volumetric capnography versus spirometry for the evaluation of pulmonary functi...
Almeida-Junior,Armando; Marson,Fernando Augusto Lima; Almeida,Celize Cruz Bresciani; Ribeiro,Maria Ângela Gonçalves Oliveira; Paschoal,Ilma AparecidaAbstract Objective: To compare the values of the markers for volumetric capnography and spirometry and their ability to classify children and adolescents with asthma, cystic fibrosis (CF), and healthy controls. Methods: This was a cross-sectional study that included 103 patients with controlled persistent allergic asthma, 53 with CF and a healthy control group with 40 volunteers (aged 6 to 15 years), of both se...
Multichannel intraluminal impedance-pH and psychometric properties in gastroeso...
Gonçalves,Emília Silva; Assumpção,Maíra Seabra de; Servidoni,Maria Fátima Correa Pimenta; Lomazi,Elizete Aparecida; Ribeiro,José DirceuAbstract Objective: Systematically assess studies that have analyzed the psychometric properties of multichannel intraluminal impedance-pH for the diagnosis of gastroesophageal reflux. Systematically verify studies that have analyzed the psychometric properties of multichannel intraluminal impedance-pH regarding the diagnosis of gastroesophageal reflux disease in pediatric patients. Methods: Systematic review c...
Avaliação do controle da asma entre diferentes medidas e avaliação da capacidad...
Matsunaga,Natasha Yumi; Oliveira,Caio de; Gianfrancesco,Livea; Oliveira,Marina Simões; Simões,Maria Cristina Ribeiro dos Santos; Morcillo,André MorenoRESUMO Objetivo Avaliar a concordância entre as medidas de controle da asma e a capacidade de exercício funcional em crianças e adolescentes com asma não controlada e controlada. Métodos Selecionamos crianças e adolescentes com asma de 7 a 17 anos, que foram atendidos no Ambulatório de Pneumologia Pediátrica da Universidade Estadual de Campinas. Todos os pacientes tiveram nível de controle da asma avaliado pelo...
Chloride and sodium ion concentrations in saliva and sweat as a method to diagn...
Gonçalves,Aline Cristina; Marson,Fernando Augusto Lima; Mendonça,Regina Maria Holanda; Bertuzzo,Carmen Sílvia; Paschoal,Ilma AparecidaAbstract Objective: Cystic fibrosis diagnosis is dependent on the chloride ion concentration in the sweat test (≥ 60 mEq/mL - recognized as the gold standard indicator for cystic fibrosis diagnosis). Moreover, the salivary glands express the CFTR protein in the same manner as sweat glands. Given this context, the objective was to verify the correlation of saliva chloride concentration and sweat chloride concent...
Microbiological contamination of nebulizers used by cystic fibrosis patients: a...
Riquena,Barbara; Monte,Luciana de Freitas Velloso; Lopes,Agnaldo José; Silva-Filho,Luiz Vicente Ribeiro Ferreira da; Damaceno,NeivaABSTRACT Objective: Home nebulizers are routinely used in the treatment of patients with cystic fibrosis (CF). This study aims to evaluate the contamination of nebulizers used for CF patients, that are chronically colonized by Pseudomonas aeruginosa, and the association of nebulizer contamination with cleaning, decontamination and drying practices. Methods: A cross-sectional, observational, multicenter study wa...
OSCILOMETRIA DE IMPULSO E ESPIROMETRIA EM ESCOLARES SUBMETIDOS AO TESTE DE CAMI...
Assumpção,Maíra Seabra de; Ribeiro,José Dirceu; Wamosy,Renata Maba Gonçalves; Parazzi,Paloma Lopes Francisco; Schivinski,Camila Isabel SantosRESUMO Objetivo: Verificar as repercussões do teste de esforço submáximo na mecânica respiratória e na função pulmonar de escolares. Métodos: Estudo transversal com escolares de 7 a 14 anos submetidos à avaliação da mecânica respiratória por sistema de oscilometria de impulso (IOS) e da função pulmonar pela espirometria. Realizou-se também o teste de caminhada de seis minutos (TC6), todos segundo os padrões da ...
Variants in the interleukin 8 gene and the response to inhaled bronchodilators ...
Furlan,Larissa Lazzarini; Ribeiro,José Dirceu; Bertuzzo,Carmen Sílvia; Salomão Junior,João Batista; Souza,Dorotéia Rossi SilvaAbstract Objective: Interleukin 8 protein promotes inflammatory responses, even in airways. The presence of interleukin 8 gene variants causes altered inflammatory responses and possibly varied responses to inhaled bronchodilators. Thus, this study analyzed the interleukin 8 variants (rs4073, rs2227306, and rs2227307) and their association with the response to inhaled bronchodilators in cystic fibrosis patients...