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Pulegone and Eugenol Oral Supplementation in Laboratory Animals: Results from A...

Ribeiro-Silva, CM; Faustino-Rocha, Ana I.; Gil da Costa, RM; Medeiros, R; Pires, MJ; Gaivão, I; Gama, A; Neuparth, MJ; Barbosa, JV; Peixoto, F

Essential oils are natural compounds used by humans for scientific purposes due to their wide range of properties. Eugenol is mostly present in clove oil, while pulegone is the main constituent of pennyroyal oil. To guarantee the safe use of eugenol and pulegone for both humans and animals, this study addressed, for the first time, the effects of these compounds, at low doses (chronic toxicity) and high doses (...


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