4 documents found, page 1 of 1
Cost effectiveness of outpatient lumbar discectomy
Linhares, D; Fonseca, JA; Ribeiro-da-Silva, M; Conceição, F; Sousa, A; Sousa-Pinto, B; Neves, NBackground: Microdiscectomy is the most commonly performed spine surgery and the first transitioning for outpatient settings. However, this transition was never studied, in what comes to cost-utility assessment. Accordingly, this economic study aims to access the cost-effectiveness of outpatient lumbar microdiscectomy when compared with the inpatient procedure. Methods: This is a cost utility study, adopting th...
“Bone-shot fracture” – An unusual iliac wing fracture caused by a projectile of...
Vieira, LP; Costa, FP; Negrão, P; Neves, N; Monteiro, EL; Ribeiro-da-Silva, MCase: A young adult male sustained a high-energy crash suffering multiple injuries including a comminuted right femoral shaft fracture and an ipsilateral iliac wing fracture. The iliac fracture was caused by a femoral fragment which was projected and pierced the iliac wing. The patient underwent surgery with retrieval of the femoral fragment and fixation of the iliac and femoral fractures. The lesions healed un...
Nociceptive mechanisms driving pain in a post-traumatic osteoarthritis mouse model
Alves, CJ; Couto, M; Sousa, DM; Magalhães, A; Neto, E; Leitão, L; Conceição, F; Monteiro, AC; Ribeiro-da-Silva, M; Lamghari, MIn osteoarthritis (OA), pain is the dominant clinical symptom, yet the therapeutic approaches remain inadequate. The knowledge of the nociceptive mechanisms in OA, which will allow to develop effective therapies for OA pain, is of utmost need. In this study, we investigated the nociceptive mechanisms involved in post-traumatic OA pain, using the destabilization of the medial meniscus (DMM) mouse model. Our resu...
Interplay between sympathetic nervous system and inflammation in aseptic loosen...
Ribeiro-da-Silva, M; Vasconcelos, DM; Alencastre, IS; Oliveira, MJ; Linhares, D; Neves, N; Costa, G; Henrique, R; Lamghari, M; Alves, CJInflammation is a common symptom in joint disorders such as rheumatoid arthritis, osteoarthritis (OA) and implant aseptic loosening (AL). The sympathetic nervous system is well known to play a critical role in regulating inflammatory conditions, and imbalanced sympathetic activity has been observed in rheumatoid arthritis. In AL it is not clear whether the sympathetic nervous system is altered. In this study we...