6 documents found, page 1 of 1
Effect of poly(ADP-ribosyl)ation inhibitors on the genotoxic effects of the bor...
Oliveira, NG; Castro, M; Rodrigues, AS; Goncalves, IC; Martins, C; Rico, JMT; Rueff, JThe boron neutron capture (BNC) reaction results from the interaction of B-10 with low-energy thermal neutrons and gives rise to highly damaging lithium and alpha-particles. In this work the genotoxicity caused by the BNC reaction in V79 Chinese hamster cells was evaluated in the presence of poly(ADP-ribosyl)ation inhibitors. Poly(ADP-ribose) polymerase-1 (PARP-1), the most important member of the PARP enzyme f...
The effect of ethanol on acrylic bone cement
Bettencourt, A; Calado, A; Amaral, J; Vale, FM; Rico, JMT; Monteiro, J; Montemor, MF; Ferreira, MGS; Castro, MProsthesis loosening is a major problem associated with the use of poly(methyl methacrylate) (PMMA) bone cement that may be related to a peri-implant vacuolisation commonly observed at bone-cement interface. Methyl methacrylate (MMA) monomer may be one of the cement components partly responsible for the mentioned vacuolisation due to a cytotoxic effect associated to this compound. Alcoholism has been related to...
The influence of vacuum mixing on methylmethacrylate liberation from acrylic ce...
Bettencourt, A; Calado, A; Amaral, J; Vale, FM; Rico, JMT; Monteiro, J; Castro, MPolymethylmethacrylate (PMMA) bone cement is a biomaterial used to anchor prostheses during joint replacement surgery. Residual methylmethacrylate monomer (MNA) may be related with the cytotoxic effect of PM MA. The aim of the present paper was to investigate the effect of two different cement mixing methods: hand stirring at atmospheric pressure and under partial vacuum (0.330 and 0.154 bar) on residual monome...
Agging effect on methylmethacrylate liberation from acrylic cement powder
Bettencourt, A; Calado, A; Amaral, J; Vale; FM; Rico, JMT; Monteiro, J; Lopes, A; Pereira, L; Castro, M
Influence of different media composition on methylmethacrylate release from acr...
Bettencourt, A; Calado, A; Amaral, J; Vale; FM; Rico, JMT; Monteiro, J; Lopes, A; Pereira, L; Castro, M
In vitro release studies of methylmethacrylate liberation from acrylic cement p...
Bettencourt, A; Calado, A; Amaral, J; Vale, FM; Rico, JMT; Monteiro, J; Lopes, A; Pereira, L; Castro, MBone cement or polymethylmethacrylate (PMMA) is commonly used for anchoring cemented prosthesis to the bone. Cytotoxic effect of culture media exposed to PMMA powder may be related with long term problems associated with acrylic cement application, being the monomer (methylmethacrylate) one of the cement's component partly responsible for the cytotoxic effect. The present work reports the studies of monomer rel...