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Gastroprotective activity of the hydroethanolic extract and ethyl acetate fract...

Sobreira, Flávia; Hernandes, Leandro Santoro; Vetore-Neto, Alberto; Díaz, Ingrit E. Collantes; Santana, Fernanda Carvalho de; Mancini-Filho, Jorge

Peptic ulcers are an important pathology, and the search for safer and more effective treatment methods is of paramount importance. In this study, we assess the gastroprotective effects of the hydroethanolic extract (HE) and ethyl acetate fraction (EAF) from Kalanchoe pinnata leaves against an ethanol/HCl-induced ulcer model in rats. The HE reduced gastric lesions by approximately 47% (400 mg/kg). A significant...

Date: 2017   |   Origin: Oasisbr

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