4 documents found, page 1 of 1
Prevalence and risk factors for latent tuberculosis infection among primary hea...
Prado,Thiago Nascimento do; Riley,Lee W.; Sanchez,Mauro; Fregona,Geisa; Nóbrega,Renata Lyrio Peres; Possuelo,Lia Gonçalves; Zandonade,ElianaHealth care workers (HCW) are at increased risk of latent tuberculosis infection (LTBI) from occupational exposure to Mycobacterium tuberculosis. The objective was to determine the prevalence of and risk factors for LTBI among primary HCW in five Brazilian cities. We conducted a cross-sectional study, from 2011 to 2013, among primary HCW, using a structured questionnaire and an evaluated for LTBI using the Quan...
Bacterial immunostat: Mycobacterium tuberculosis lipids and their role in the h...
Queiroz,Adriano; Riley,Lee W.Abstract: The lipid-rich cell wall of Mycobacterium tuberculosis is a dynamic structure that is involved in the regulation of the transport of nutrients, toxic host-cell effector molecules, and anti-tuberculosis drugs. It is therefore postulated to contribute to the long-term bacterial survival in an infected human host. Accumulating evidence suggests that M. tuberculosis remodels the lipid composition of the c...
Clinical and epidemiological characteristics associated with unfavorable tuberc...
Prado,Thiago Nascimento do; Rajan,Jayant V.; Miranda,Angélica Espinosa; Dias,Elias dos Santos; Cosme,Lorrayne Beliqui; Possuelo,Lia GonçalvesAbstract Background: TB patients co-infected with HIV have worse treatment outcomes than non-coinfected patients. How clinical characteristics of TB and socioeconomic characteristics influence these outcomes is poorly understood. Here, we use polytomous regression analysis to identify clinical and epidemiological characteristics associated with unfavorable treatment outcomes among TB-HIV co-infected patients in...
blaGES carrying Pseudomonas aeruginosa isolates from a public hospital in Rio d...
Pellegrino,Flávia L. P. C.; Netto-dos Santos,Kátia R.; Riley,Lee W.; Moreira,Beatriz M.Previous analysis of Pseudomonas aeruginosa class-1 integrons from Rio de Janeiro, Brazil, revealed the blaGES gene in one isolate. We screened isolates of two widespread PFGE genotypes, A and B, at a public hospital in Rio, for the presence of blaGES. The gene was detected in all seven P. aeruginosa isolates belonging to genotype B. Three of the seven genotype-B isolates were resistant to amikacin, aztreonam, ...