3 documents found, page 1 of 1
Bone phenotyping approaches in human, mice and zebrafish : expert overview of t...
Foessl, Ines; Bassett, J. H. Duncan; Bjørnerem, Åshild; Busse, Björn; Calado, Ângelo; Chavassieux, Pascale; Christou, Maria; Douni, EleniA synoptic overview of scientific methods applied in bone and associated research fields across species has yet to be published. Experts from the EU Cost Action GEMSTONE ("GEnomics of MusculoSkeletal Traits translational Network") Working Group 2 present an overview of the routine techniques as well as clinical and research approaches employed to characterize bone phenotypes in humans and selected animal models...
Osteoblast-derived NOTUM reduces cortical bone mass in mice and the NOTUM locus...
Movérare-Skrtic, Sofia; Nilsson, Karin H.; Henning, Petra; Funck-Brentano, Thomas; Nethander, Maria; Rivadeneira, FernandoMade available in DSpace on 2020-12-12T00:55:20Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-10-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Dementia Collaborative Research Centres, Australia; Deutsche Forschungsgemeinschaft; Novo Nordisk Fonden; Stiftelsen för Strategisk Forskning; Vetenskapsrådet; IngaBritt och Arne Lundbergs Forskningsstiftelse; Osteoporosis is a common ...
Genome-wide association analyses identify new risk variants and the genetic arc...
van Rheenen, Wouter; Shatunov, Aleksey; Dekker, Annelot M.; McLaughlin, Russell L.; Diekstra, Frank P.; Pulit, Sara L.; van der Spek, Rick A. A.To elucidate the genetic architecture of amyotrophic lateral sclerosis (ALS) and find associated loci, we assembled a custom imputation reference panel from whole-genome-sequenced patients with ALS and matched controls (n = 1,861). Through imputation and mixed-model association analysis in 12,577 cases and 23,475 controls, combined with 2,579 cases and 2,767 controls in an independent replication cohort, we fin...