43 documents found, page 1 of 5

Sustainable synthesis, antiproliferative and acetylcholinesterase inhibition of...

This work describes the design, sustainable synthesis, evaluation of electrochemical and biological properties against HepG2 cell lines, and AChE enzymes of different substituted derivatives of 1,4- and 1,2-naphthoquinones (NQ). A microwave-assisted protocol was optimized with success for the synthesis of the 2-substituted-1,4-NQ series and extended to the 4-substituted-1,2-NQ family, providing an alternative a...

A wide array of lignin-related phenolics are oxidized by an evolved bacterial d...

Lignin is the second most abundant natural polymer next to cellulose and by far the largest renewable source of aromatic compounds on the planet. Dye-decolourising peroxidases (DyPs) are biocatalysts with immense potential in lignocellulose biorefineries to valorize emerging lignin building blocks for environmentally friendly chemicals and materials. This work investigates the catalytic potential of the enginee...

ProGreS 2nd Workshop: from biomass characterization to process synthesis (book ...

Improvement of glycaemia and endothelial function by a new low-dose curcuminoid...

Curcumin has been suggested as a promising treatment for metabolic diseases, but the high doses required limit its therapeutic use. In this study, a new curcuminoid is synthesised to increase curcumin anti-inflammatory and antioxidant potential and to achieve hypoglycaemic and protective vascular effects in type 2 diabetic rats in a lower dose. In vitro, the anti-inflammatory effect was determined through the G...

Optimization of oil recovery from Japonica luna rice bran by supercritical carb...

This study presents an optimization strategy for recovery of oil from Japonica Luna rice bran using supercritical carbon dioxide (scCO2), based on design of experiments (DoE). Initially, a 24−1 two level fractional factorial design (FFD) was used, and pressure, temperature, and scCO2 flow rate were determined as the significant variables; while the yield, total flavonoids content (TFC), and total polyphenols co...

Microwave-assisted extraction of phenolic compounds from spent coffee grounds. ...

In this study, sustainable technology microwave-assisted extraction (MAE) in association with green solvents was applied to recover phenolic compounds from spent coffee grounds (SCGs). A design of experiments (DOE) was used for process optimization. Initially, a 2(4-1) two level Fractional Factorial Design was used and ratios "solvent to solute" and "ethanol to water" were identified as the significant experime...

Bacterial laccases: some recent advances and applications

Laccases belong to the large family of multi-copper oxidases (MCOs) that couple the one-electron oxidation of substrates with the four-electron reduction of molecular oxygen to water. Because of their high relative non-specific oxidation capacity particularly on phenols and aromatic amines as well as the lack of requirement for expensive organic cofactors, they have found application in a large number of biotec...

Modelling the kinetics of supercritical CO2 extraction of biomass

This work addresses the modelling and simulation of the kinetics of CO2 supercritical extraction of oils from biomass. Experimental and simulation results from different matrices and models are presented. gPROMS Model Builder is used to find solutions to three different models applied to study the extraction of three different volatile oils from aromatic plants (coriander, fennel and savoury), and from a biores...

Influence of co-solvents on the supercritical extraction kinetics of spent coff...

Coffee is one of the most widely used beverages. An estimated 3.5 billion cups of coffee are drunk worldwide every day. In EU alone, for the period 2011-2013, 2.5 Mt of coffee were consumed. Taking into consideration that the production of coffee in 2015 was approximately 9 Mt and that from each kg of coffee 0.91 kg of solid waste is produced, the importance of a further valorization of this residue becomes obv...

Supercritical CO2 extraction of feed stocks to generate high added value bio-pr...

The huge amounts of waste generated every year by the industry, in addition to the great loss of valuable materials, pose serious organisational problems, both from an economic and ecological point of view. Many of the residues, however, have the potential to be reused and utilized completely via integrated bio-refining technologies. Extraction techniques which play a very important part in biorefineries should...