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Molecular responses in the intestine of Atlantic salmon (Salmo salar) following...

Gaetano, Pasqualina; Fernandes Duarte, Vilma Vanessa; Striberny, Anja; Hazlerigg, David G.; Jørgensen, Even H.; Campinho, Marco António; Fuentes, Juan

The transfer to seawater (SW) represents a critical stage in the production of Atlantic salmon. The success of the transfer links with the optimal development of hypo-osmoregulatory capacities during smoltification. While various strategies are adopted in aquaculture to stimulate smoltification, considerable fish loss still occurs after transfer to sea cages. Therefore, we investigated the molecular responses i...


Molecular responses in the intestine of Atlantic Salmon (Salmo salar) following...

Gaetano, Pasqualina; Fernandes Duarte, Vilma Vanessa; Striberny, Anja; Hazlerigg, David G.; Jørgensen, Even H.; Campinho, Marco António; Fuentes, Juan

The transfer to seawater (SW) represents a critical stage in the production of Atlantic salmon. The success of the transfer links with the optimal development of hypo-osmoregulatory capacities during smoltification. While various strategies are adopted in aquaculture to stimulate smoltification, considerable fish loss still occurs after transfer to sea cages. Therefore, we investigated the molecular responses i...


High plant protein diet impairs growth performance and intestinal integrity in ...

Fuentes, Juan; Fonseca, Filomena; Gregorio, Silvia; Kussaba Miguel, Larissa; Perera, Erick; Alarcón-López, Francisco J.; Martos-Sitcha, Juan A.

The Mediterranean aquaculture industry that produces mainly seabream and seabass is exploring alternative plant-based protein sources for fish feeds together with the diversification of fish species. Effective plant-based formulations require diverse sources and additives to maintain fish welfare and growth, which is especially important for carnivorous species. In this scenario, the objective of the present st...


Editorial: Endocrine regulation and physiological adaptation of stress response...

Li, Yiming; Li, Yi-Feng; Campinho, Marco António; Fuentes, Juan

Organismal growth is a complex, genetically regulated process that integrates various physiological signaling pathways, where endocrine regulation is pivotal. In fully developed animals, endocrine regulation plays a central role in maintaining homeostasis and adapting to changing environmental and biological conditions. In aquatic organisms, environmental stressors such as environmental temperature, hypoxia, sa...


Oral cortisol and dexamethasone intake: Differential physiology and transcripti...

Barany, A.; Fuentes, Juan; Valderrama, V.; Broz-Ruiz, A.; Martínez-Rodríguez, G.; Mancera, J. M.

This study approached the long-term oral administration of cortisol (F) and dexamethasone (DEX), two synthetic glucocorticoids, compared to a control group (CT) in the juveniles of a marine teleost, the gilthead seabream (Sparus aurata). Physiologically, DEX treatment impaired growth, which appears to be linked to carbohydrate allocation in muscle and liver, hepatic triglycerides depletion, and reduced hematocr...


From invasion to fish fodder: inclusion of the brown algae rugulopteryx okamura...

Fonseca, Filomena; Fuentes, Juan; Vizcaíno, Antonio Jesús; Alarcón, Francisco Javier; Mancera, Juan Miguel; Martínez-Rodríguez, Gonzalo

In keeping with the premises of Blue Circular Economy in the European Union, the present study explored the possibility of using the invasive brown alga Rugulopteryx okamurae in aquafeeds for European sea bass (Dicen-trarchus labrax). Assuming the raw algae biomass could negatively impact animal performance, four experi-mental formulations were prepared, by including macroalgae material at 5%, using crude (CR),...


Modulation of intestinal growth and differentiation by photoperiod and dietary ...

Fernandes Duarte, Vilma Vanessa; Gaetano, Pasqualina; Striberny, Anja; Hazlerigg, David; Jørgensen, Even H.; Fuentes, Juan; Campinho, Marco António

Atlantic salmon undergo smoltification, a process that prepares the fish to enter and thrive in seawater (SW). Several physiological changes occur during smolting, especially in osmoregulatory tissues, the gill, the kidney, and the intestine. Here we characterized the effects on intestinal morphogenesis of two different, commonly used smoltification regimes during the end of the freshwater phase, photoperiod an...


Editorial: microbiome dynamics as biomarkers of welfare status in aquatic species

Fonseca, Filomena; Fuentes, Juan

The importance of the microbiome in aquaculture species is widely acknowledged. The fish gut microbiota is essential for host fitness, modulated by diet and environment, and affects animal physiology. The gut microbiome optimizes nutrient uptake and immunomodulation and enhances host resilience against infectious diseases. Understanding microbiome dynamics in aquaculture species is vital in promoting animal hea...


Photoperiod and dietary treatment in freshwater modulate the short-term intesti...

Gaetano, Pasqualina; Fernandes Duarte, Vilma Vanessa; Striberny, Anja; Hazlerigg, David; Jørgensen, Even H.; Campinho, Marco António; Fuentes, Juan

Stimulation and timing of smoltification are essential for successful Atlantic salmon (Salmo salar) aquaculture. This study investigated intestinal responses during dietary and photoperiod manipulation in freshwater (FW) and after a subsequent seven days residence in seawater (SW). "Small" and "large" Atlantic salmon parr (-40 g and -130 g respectively) were treated in FW for 12 weeks and thereafter transferred...


Agouti overexpression in a transgenic model regulates integrity, permeability a...

Leal, Esther; Angotzi, Anna Rita; Godino-Gimeno, Alejandra; Gregorio, Silvia F.; Rotllant, Josep; Saera-Vila, Alfonso; Fuentes, Juan

Overexpression of asip1 in transgenic zebrafish disrupts dorsoventral pigment pattern in addition to increasing food intake levels and linear growth. A higher feed intake is unnecessary in transgenic fish to enable larger and heavier growth. A plausible explanation may rely on the enhanced feeding efficiency mediated by improved nutrient absorption in transgenic animals. To test this hypothesis, wide scope tran...


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