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Longitudinal evaluation of regulatory T-cell dynamics on HIV-infected individua...

Nobrega, Claudia; Horta, Ana Maria Lacerda Morgado Fernandes Carvalho Aboim; Teixeira, Vítor Emanuel Coutinho; Martins-Ribeiro, Ana

Objectives: A sizeable percentage of individuals infected by HIV and on antiretroviral therapy (ART) fail to increase their CD4+ T-cells to satisfactory levels. The percentage of regulatory T-cells (Tregs) has been suggested to contribute to this impairment. This study aimed to address this question and to expand the analysis of Tregs subpopulations during ART. Design: Longitudinal follow-up of 81 HIV-infected ...


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