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Systematic literature review to inform the Portuguese recommendations for the m...

Costa, Emanuel; Cunha-Santos, Filipe; Dourado, Eduardo; Oliveira, Daniela; Falzon, Louise; Romão, Vasco; Duarte, Ana Catarina; Cordeiro, Ana

OBJECTIVE: To perform a systematic literature review (SLR) aimed at evaluating the efficacy and safety of pharmacological and non-pharmacological treatments for Raynaud's phenomenon (RP) and digital ulcers (DU) in patients with systemic sclerosis (SSc) and other connective tissue diseases (CTD), in order to inform the Portuguese recommendations for managing RP and DU in these patients. METHODS: A SLR was conduc...


Reuma.pt/vasculitis - the Portuguese vasculitis registry

Ponte, Cristina; Khmelinskii, Nikita; Teixeira, Vítor; Luz, Karine; Peixoto, Daniela; Rodrigues, Marília; Luís, Mariana; Teixeira, Lídia; Sousa, Sandra

BACKGROUND: The vasculitides are a group of rare diseases with different manifestations and outcomes. New therapeutic options have led to the need for long-term registries. The Rheumatic Diseases Portuguese Register, Reuma.pt, is a web-based electronic clinical record, created in 2008, which currently includes specific modules for 12 diseases and > 20,000 patients registered from 79 rheumatology centres. On Oct...


Portuguese recommendations for the use of methotrexate in rheumatic diseases - ...

Duarte, Ana Catarina; Santos-Faria, Daniela; Gonçalves, Maria João; Sepriano, Alexandre; Mourão, Ana Filipa; Duarte, Cátia; Neves, Joana Sousa

BACKGROUND: Methotrexate (MTX) is the first-line drug in the treatment of rheumatoid arthritis (RA) and the most commonly prescribed disease modifying anti-rheumatic drug. Moreover, it is also used as an adjuvant drug in patients under biologic therapies, enhancing the efficacy of biologic agents. OBJECTIVES: To review the literature and update the Portuguese recommendations for the use of MTX in rheumatic dise...


Portuguese guide lines for the use of biological agents in rheumatoid arthritis...

Fonseca, João Eurico; Bernardes, Miguel; Canhão, Helena; Santos, Maria José; Quintal, Alberto; Malcata, Armando; Neto, Adriano; Cordeiro, Ana

The authors present the revised version of the Portuguese Society of Rheumatology (SPR) guidelines for the treatment of Rheumatoid Arthritis (RA) with biological therapies. In these guidelines the criteria for introduction and maintenance of biological agents are discussed as well as the contraindications and procedures in the case of non-responders. Biological treatment (with a tumour necrosis factor antagonis...


Guia prático de utilização de terapêuticas biotecnológicas na artrite reumatóid...

Mourão, Ana Filipa; Fonseca, João Eurico; Canhão, Helena; Santos, Maria José; Bernardo, Alexandra; Cordeiro, Ana; Cravo, Ana Rita; Ribeiro, Ana

The authors review the practical aspects of biologi -cal therapy use for rheumatoid arthritis patients, commenting safety issues before and after treatment initiation and the best treatment strategies to optimize efficacy.


Recomendações portuguesas «como diagnosticar, monitorizar e tratar a artrite pe...

Ribeiro, Ana; Machado, Pedro; Ramiro, Sofia; Duarte, Cátia; Mourão, Ana Filipa; Bogas, Mónica; Costa, Maria Lúcia; Bernardes, Miguel; Santos, Maria José

Objective: The 3E (Evidence, Expertise, Exchange) Initiative is a multinational effort of rheumatologists aimed at developing evidence-based recommendations addressing specific questions relevant to clinical practice. The objective of the Portuguese contribution for the 3E Initiative was to develop evidence-based recommendations on how to investigate, follow-up and treat undifferentiated peripheral inflammatory...


Recomendações portuguesas para utilização de metotrexato no tratamento de doenç...

Canhão, Helena; Santos, Maria José; Costa, Maria Lúcia; Bogas, Mónica; Mourão, Ana Filipa; Machado, Pedro; Fonseca, João Eurico

Objectives:To develop Portuguese evidence-based recommendations for the use of methotrexate (MTX) in daily clinical practice in rheumatic disorders. Methods:The Portuguese project was integrated in the multinational 3E Initiative (Evidence, Expertise, Exchange) 2007-2008 where a total of 751 rheumatologists from 17 countries have participated. Ten clinical questions concerning the use of MTX in rheumatic diseas...


Guia prático de utilização de terapêuticas de biotecnologia na artrite reumatóide

Fonseca, Joao Eurico; Canas Silva, J. A.; Canhão, Helena; Santos, Maria Jose; Barcelos, Anabela; Ines, Luis; Costa, Maria Lucia; Rodrigues, Mario


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