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Evaluation of urinary cysteinyl leukotrienes as biomarkers of severity and puta...

Reina-Couto, M; Roboredo-Madeira, M; Pereira-Terra, P; Silva-Pereira, C; Martins, S; Teixeira-Santos, L; Pinho, D; Dias, A; Cordeiro, G; Dias, CC

Background Cysteinyl leukotrienes (CysLT) are potent inflammation-promoting mediators, but remain scarcely explored in COVID-19. We evaluated urinary CysLT (U-CysLT) relationship with disease severity and their usefulness for prognostication in hospitalized COVID-19 patients. The impact on U-CysLT of veno-venous extracorporeal membrane oxygenation (VV-ECMO) and of comorbidities such as hypertension and obesity ...


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