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Activity of Diphenyl diselenide against Aspergillus isolates

Melo, Aryse Martins; Poester, Vanice Rodrigues; Munhoz, Lívia; Trápaga, Mariana; Roca, Beatriz; Klafke, Gabriel Baracy; Sabino, Raquel

Organoselenium compounds have been showing promising antimicrobial activity against bacteria and some fungal species. Among these compounds, diphenyl diselenide (PhSe)2 is a simple and chemically stable molecule with proven low toxicity to animal hosts. Although the mechanisms of action of this molecule are not totally clear, it has been reported that it has a prooxidative activity for microorganisms, due to gl...

Date: 2020   |   Origin: Repositório Científico do Instituto Nacional de Saúde
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