Enquadramento: Atualmente, a população tende a optar cada vez mais por alimentos processados devido à falta de tempo e fácil acesso. Estes alimentos, ricos em gorduras saturadas, açúcares e calorias, e com baixo teor em nutrientes, são uma das principais causas de doenças, como a hipertensão e diabetes [1]. Assim, as algas marinhas têm surgido como uma opção saudável na alimentação, devido ao seu elevado teor n...
Enquadramento: A problemática da poluição ambiental é atual, uma vez que, por exemplo, as águas residuais contendo diversas concentrações de metais pesados, poluentes orgânicos e nutrientes (ex: carbono, azoto e fósforo) continuam a ser despejadas em áreas costeiras, causando degradação ambiental [1]. Desta forma, a procura de soluções sustentáveis é crucial. O processo de biorremediação consiste em remover com...
Fiber-based constructs have been produced as an alternative to conventional dressings for the treatment of chronic wounds (CWs), showing good tenability, high surface area and regulable porosity. A commonly used technique for processing such dressings is wet-spinning, which involves precipitating a polymer solution into a coagulation bath containing a non-solvent of that polymer. This process produces fibers wi...
Diabetic foot ulcers (DFUs) are a serious complication of diabetes, often resulting in infections and further health deterioration. Thus, the development of an approach combining different therapies in just one formulation to treat DFUs remains very challenging. Silver-plated polyamide fibers offer antimicrobial properties, while lyocell provides biodegradability, biocompatibility and moisture management abilit...
Skin hyperpigmentation disorders, such as melasma, are linked to excessive melanin production, primarily regulated by the enzyme tyrosinase (TYR). While current inhibitors like kojic acid (KA) are effective, they often cause adverse side effects, driving the search for safer andnatural alternatives. This study evaluated the TYR inhibitory potential of bioactive-rich extracts from acorn, cocoa, cork, and eucalyp...
This research aims to explore the potential benefits of natural deep eutectic solvents (NADES) in formulating translucent NADES-in-oil emulsions (TEs) containing essential oils (EOs) for cosmetic applications. The TEs investigated in this study are based on previous formulations, consisting of 50 wt.% egg phosphatidylcholine (EPC), 20 wt.% ethanol, 20 wt.% olive oil (OlO), thyme oil (TO), or oregano oil (OrO), ...
Chronic wounds (CWs) are labeled as a significant clinical challenge due to their complex treatment, often hindered by bacterial colonization and persistent inflammation. In this study, the potential of wet-spun polycaprolactone (PCL) fibers embedded with thymol (PCL-thy), a natural antibacterial, anti-inflammatory and antioxidant compound, was investigated for the treatment of CWs. The incorporation of thymol ...
Four deep eutectic mixtures (DES) with varying water concentrations (10% to 50%) were synthesized using naturally derived and biodegradable components: choline chloride:urea (ChCl:U), choline chloride:levulinic acid (ChCl:Lev), betaine:levulinic acid (Bet:Lev), and glycerol:phosphoric acid (Gly:Ph). These ternary mixtures, designed as greener alternatives to conventional solvents, were tested as substitutes of ...
Grape pomace, a major wine industry byproduct, is rich in bioactive compounds and increasingly explored for sustainable valorization. However, lacking proper storage, this matrix may become contaminated with ochratoxin A (OTA), a nephrotoxic and potentially carcinogenic mycotoxin produced by Aspergillus and Penicillium species commonly found in grapes, wine, and their byproducts. This study investigates grape p...