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Enzyme activities of brown trout liver and kidney peroxisomes after paraquat ex...

Resende, Albina Dolores; Lobo da Cunha, Alexandre; Rocha, Eduardo

Paraquat, a potent herbicide, can be highly toxic to fish, causing morphological and biochemical alterations in several organs, including induction of oxidative stress that may result in cellular damage. Since peroxisomes are vital regulators of reactive oxygen species, it was hypothesized that a subacute exposure of brown trout – a sensitive bioindicator – to a waterborne environmentally relevant concentration...

Date: 2025   |   Origin: Scientific Letters

Subcellular distribution of some purine catabolism enzymes in brown trout (Salm...

Resende, Albina Dolores; Rocha, Eduardo; Lobo-da-Cunha, Alexandre

Background: Subcellular location of purine catabolism enzymes is of great interest in comparative studies due to the significant variability among species [1]. This metabolic pathway reflects in large extent a phylogenetic evolution with the loss of several enzymes in certain species, resulting in differences in the end products that are excreted [2]. Particularly in fishes, some of those enzymes are described ...

Date: 2024   |   Origin: Scientific Letters

Effects and Mechanisms of Action of Preussin, a Marine Fungal Metabolite, again...

Seabra, Rosária; Malhão, Fernanda; Correia, Alexandra; Costa, Carla; Kijjoa, Anake; Rocha, Eduardo

Triple-negative breast cancer (TNBC) represents an aggressive subtype of breast cancer (BC) with a typically poorer prognosis than other subtypes of BC and limited therapeutic options. Therefore, new drugs would be particularly welcome to help treat TNBC. Preussin, isolated from the marine sponge-associated fungus, Aspergillus candidus, has shown the potential to reduce cell viability and proliferation as well ...


Fucoxanthin Holds Potential to Become a Drug Adjuvant in Breast Cancer Treatmen...

Malhão, Fernanda; Macedo, Ana Catarina; Costa, Carla; Rocha, Eduardo; Ramos, Alice Abreu

Fucoxanthin (Fx) is a carotenoid derived from marine organisms that exhibits anticancer activities. However, its role as a potential drug adjuvant in breast cancer (BC) treatment is still poorly explored. Firstly, this study investigated the cytotoxic effects of Fx alone and combined with doxorubicin (Dox) and cisplatin (Cis) on a panel of 2D-cultured BC cell lines (MCF7, SKBR3 and MDA-MB-231) and one non-tumor...


Abandono de estações férreas: cartografia nas cidades de Jaguarão e Rio Branco ...

Forneck, Vanessa; Rocha, Eduardo

Durante quase um século, as estações férreas funcionaram como ponto de embarque e desembarque de passageiros. Por volta de 1990 ocorre a interrupção de seu uso original e as edificações tornaram-se obsoletas e, por consequência, criaram-se territórios abandonados. Neste trabalho, busca-se explorar os territórios no entorno das estações férreas abandonadas, analisando as relações dessas edificações com quem habi...

Date: 2020   |   Origin: Oasisbr

Literatura e a cidade: intertextos, cartografia das imagens expressa em palavras.

Soares, Bianca Ramires; Rocha, Eduardo

Submitted by Simone Maisonave (simonemaisonave@hotmail.com) on 2020-06-26T23:47:33Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Literatura_e_a_cidade.pdf: 167930 bytes, checksum: e1c5f1eb102c4c56ea259e5d545208d2 (MD5); Approved for entry into archive by Aline Batista (alinehb.ufpel@gmail.com) on 2020-06-29T12:51:11Z (GMT) No. of bitstreams: 2 Literatura_e_a_cidade...

Date: 2020   |   Origin: Oasisbr

Heterotopias na cidade: análise cartografica do evento "Sofá na Rua" em Pelotas.

Sebalhos, Carolina Frasson; Rocha, Eduardo

Submitted by Simone Maisonave (simonemaisonave@hotmail.com) on 2020-06-27T00:01:16Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) HETEROTOPIAS_NA_CIDADE.pdf: 401118 bytes, checksum: 4de8c99984a4e0888f7162a9a07e894c (MD5); Approved for entry into archive by Aline Batista (alinehb.ufpel@gmail.com) on 2020-06-29T12:51:30Z (GMT) No. of bitstreams: 2 HETEROTOPIAS_NA_CIDA...

Date: 2020   |   Origin: Oasisbr

Abandono de povoados: Minas do Camaquã e Minas Corrales na fronteira Brasil-Uru...

Portela, Laís Dellinghausen; Rocha, Eduardo

Submitted by Simone Maisonave (simonemaisonave@hotmail.com) on 2020-06-27T01:25:19Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) ABANDONO_DE_POVOADOS.pdf: 175939 bytes, checksum: 1d039eb03de136b12a07bf3d33f3cf7e (MD5); Approved for entry into archive by Aline Batista (alinehb.ufpel@gmail.com) on 2020-06-29T12:52:45Z (GMT) No. of bitstreams: 2 ABANDONO_DE_POVOADOS.p...

Date: 2020   |   Origin: Oasisbr

Ocupações urbanas desviantes e disciplinadas na linha de fronteira Brasil-Uruguay.

Resende, Lorena Maia; Rocha, Eduardo

Submitted by Simone Maisonave (simonemaisonave@hotmail.com) on 2020-06-27T01:56:47Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) OCUPACOES_URBANAS_DESVIANTES_E_DISCIPLINADAS.pdf: 400114 bytes, checksum: cda95bea14b37389ff94ed90e145012c (MD5); Approved for entry into archive by Aline Batista (alinehb.ufpel@gmail.com) on 2020-06-29T12:53:15Z (GMT) No. of bitstreams: ...

Date: 2020   |   Origin: Oasisbr

Seres lentos e vida urbana: caminhografia pelas ruas de Porto Alegre, Montevide...

Santos, Taís Beltrame dos; Rocha, Eduardo

Submitted by Simone Maisonave (simonemaisonave@hotmail.com) on 2020-06-27T19:59:46Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) SERES_LENTOS_E_VIDA_URBANA.pdf: 195741 bytes, checksum: 1ee54498b562f27b8e09f193f30ea1dd (MD5); Approved for entry into archive by Aline Batista (alinehb.ufpel@gmail.com) on 2020-06-29T12:55:20Z (GMT) No. of bitstreams: 2 SERES_LENTOS_E_V...

Date: 2020   |   Origin: Oasisbr

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