113 documents found, page 1 of 12
Interactions between Insomnia, Sleep Disordered Breathing and Cardiometabolic R...
Meira e Cruz, Miguel; Gozal, David; Salles, Cristina; Rocha, Isabel; Ettlin, DominikThe existence of intersected pathways between the mechanisms of insomnia, sleep-disordered breathing and persistent/chronic pain has been documented. Such concurrence will eventually contribute to a higher burden of cardiometabolic diseases, a main cause of death worldwide. The aim of this study was to evaluate the interactions between insomnia, sleep-disordered breathing, cardiometabolic risk, and psychosocial...
Interactions between insomnia, sleep disordered breathing and cardiometabolic r...
Meira e Cruz, Miguel; Gozal, David; Salles, Cristina; Rocha, Isabel; Ettlin, DominikThe existence of intersected pathways between the mechanisms of insomnia, sleep-disordered breathing and persistent/chronic pain has been documented. Such concurrence will eventually contribute to a higher burden of cardiometabolic diseases, a main cause of death worldwide. The aim of this study was to evaluate the interactions between insomnia, sleep-disordered breathing, cardiometabolic risk, and psychosocial...
Lead as an environmental toxicant in models of synucleinopathies
Shvachiy, Liana; Amaro-Leal, Ângela; Machado, Filipa; Rocha, Isabel; Geraldes, Vera; Outeiro, TiagoLead, a toxic heavy metal, is prevalent in various industrial applications, contributing to environmental contamination and significant health concerns. Lead affects various body systems, especially the brain, causing long-lasting cognitive and behavioral changes. While most studies have focused on continuous lead exposure, intermittent exposure, such as that caused by migration or relocations, has received les...
Influence of brainstem’s area A5 on sympathetic outflow and cardiorespiratory d...
Rocha, Isabel; González-García, Marta; Carrillo-Franco, Laura; Dawid-Milner, Marc Stefan; López-González, Manuel VictorArea A5 is a noradrenergic cell group in the brain stem characterised by its important role in triggering sympathetic activity, exerting a profound influence on the sympathetic outflow, which is instrumental in the modulation of cardiovascular functions, stress responses and various other physiological processes that are crucial for adaptation and survival mechanisms. Understanding the role of area A5, therefor...
Autonomic nervous system education in Europe: EAN/EFAS/INUS survey on curricula...
Reis‐Carneiro, Diogo; Skoric, Magdalena Krbot; Habek, Mario; Adamec, Ivan; Calandra‐Buonaura, Giovanna; Cortelli, Pietro; van Dijk, J. GertBackground and purpose: Centers for training in autonomic nervous system (ANS) disorders are not widely available and the recent coronavirus 2019 pandemic temporarily reduced training opportunities in autonomic medicine across European countries. Here we evaluated the current state of education, clinical skills and postgraduate educational preferences on ANS disorders of European neurology residents and consult...
Clinical presentation and management strategies of cardiovascular autonomic dys...
Carneiro, Diogo Reis; Rocha, Isabel; Habek, Mario; Helbok, Raimund; Sellner, Johann; Struhal, Walter; Wenning, Gregor; Fanciulli, AlessandraBackground: Cardiovascular autonomic dysfunction may reportedly occur after a coronavirus-disease- 2019 (COVID-19) infection, but the available evidence is scattered. Here we sought to understand the acute and mid-term effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV- 2) infection on cardiovascular autonomic function. Methods: We performed a systematic PubMed, Embase, Web of Science, medRxiv...
The first multi-tissue genome-scale metabolic model of a woody plant highlights...
Cunha, Emanuel Rodrigues; Silva, Miguel; Chaves, Inês; Demirci, Huseyin; Lagoa, Davide Rafael Santos; Lima, Diogo; Rocha, Miguel; Rocha, IsabelOver the last decade, genome-scale metabolic models have been increasingly used to study plant metabolic behaviour at the tissue and multi-tissue level under different environmental conditions. Quercus suber, also known as the cork oak tree, is one of the most important forest communities of the Mediterranean/Iberian region. In this work, we present the genome-scale metabolic model of the Q. suber (iEC7871). Th...
Clinical presentation and management strategies of cardiovascular autonomic dys...
Reis Carneiro, Diogo; Rocha, Isabel; Habek, Mario; Helbok, Raimund; Sellner, Johann; Struhal, Walter; Wenning, Gregor; Fanciulli, AlessandraBackground: Cardiovascular autonomic dysfunction may reportedly occur after a coronavirus-disease-2019 (COVID-19) infection, but the available evidence is scattered. Here we sought to understand the acute and mid-term effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on cardiovascular autonomic function. Methods: We performed a systematic PubMed, Embase, Web of Science, medRxiv, ...
EFAS/EAN survey on the influence of the COVID-19 pandemic on European clinical ...
Fanciulli, Alessandra; Skorić, Magdalena Krbot; Leys, Fabian; Carneiro, Diogo Reis; Campese, Nicole; Calandra-Buonaura, Giovanna; Camaradou, JenniferPurpose: To understand the influence of the coronavirus disease 2019 (COVID-19) pandemic on clinical autonomic education and research in Europe. Methods: We invited 84 European autonomic centers to complete an online survey, recorded the pre-pandemic-to-pandemic percentage of junior participants in the annual congresses of the European Federation of Autonomic Societies (EFAS) and European Academy of Neurology (...
Orthostatic stress and baroreflex sensitivity: a window into autonomic dysfunct...
Ferreira, Mónica; Laranjo, Sergio; Cunha, Pedro; Geraldes, Vera; Oliveira, Mario; Rocha, IsabelThe abnormal neural control of atria has been considered one of the mechanisms of paroxysmal atrial fibrillation (PAF) pathogenesis. The baroreceptor reflex has an important role in cardiovascular regulation and may serve as an index of autonomic function. This study aimed to analyze the baroreceptor reflex's role in heart rate regulation during upright tilt (HUT) in patients with lone PAF. The study included 6...