91 documents found, page 1 of 10
Impact of fixed vs. variable DC-Link voltages on maximizing efficiency of EVs f...
Amin, Saghir; Awais, Muhammad; Rocha, Joao; Afonso, João L.; Costa, Nuno; Monteiro, Vítor Duarte FernandesIn this study, the effect of the DC-link voltage on the efficiency of a two-stage converter system used in an electric vehicle (EV) fast-charging systems is presented. The rectification is performed in the first stage by means of an AC/DC three-phase three-level T-type converter (3P3L-T-type), and the second stage consists of a two-stage DC/DC converter that charges the EV battery. A comprehensive analysis of t...
NILAB. Nile as Laboratory
Rocha, Joao; Ferrari, Marco; Sá, JorgeThe Ministry of Culture pays great attention to participating in important International Forums, to highlight the civilized image of Egypt, its Ancient Culture and Arts. The Venice Biennale is one of the most important gateways overlooking the International Cultural scene, and the Architecture Biennale is a predominant opportunity to display Egyptians’ creativity, ideas, new and innovative Architectural visions...
Experimental Murine Models for Colorectal Cancer Research
Neto, Íris; Rocha, Joao; Gaspar, Maria Manuela; Reis, CatarinaSimple Summary In its early stages, colorectal cancer (CRC) is a localized tumor, but when it metastasizes, it has dramatic consequences. Murine models in CRC research are important tools for advancing the knowledge in diagnostic and treatment of this pathology. The present review aims to provide a variety of murine models in CRC research describing their particular advantages and drawbacks. Abstract Colorectal...
ARCHITECTURE TOURISM AND MARGINAL AREAS RESEARCH AND DESIGN PROPOSALS
Rocha, Joao; Bertini, ViolaWhat is the role of architecture when enhancing tourism in a region? How can the architect’s vision help reactivate under performing regions, considering the relationship between design, heritage, tourism and landscape? How can design’s architectural and landscape processes contribute to the reinvention of marginal areas, reflect upon the sense of place and the needs expressed by visitors, while prioritizing th...
Atlas Marrakech. Musei per la città storica
Ferrari, Marco; Rocha, Joao; Ferrara, PietroO livro Atlas Marrakech. Musei per la città storica, de coautoria do Prof. João Rocha, diretor do Departamento de Arquitetura, é lançado esta semana, sintetizando investigação realizada sobre Marrakech e representando o resultado da lecionação de uma Unidade Curricular de Projeto na Università Iuav de Veneza, onde a cidade de Marrakech foi o objeto de estudo. O livro, apresenta textos dos três autores, Marco Fe...
Spiro-ß-lactam BSS-730A Displays Potent Activity against HIV and Plasmodium
Bártolo, Inês; Santos, Bruna S.; Fontinha, Diana; Machado, Marta; Francisco, Denise; Sepodes, Bruno; Rocha, Joao; Mota-Filipe, Hélder; Pinto, RuiThe high burden of malaria and HIV/AIDS prevents economic and social progress in developing countries. A continuing need exists for development of novel drugs and treatment regimens for both diseases in order to address the tolerability and long-term safety concerns associated with current treatment options and the emergence of drug resistance. We describe new spiro-β-lactam derivatives with potent (nM) activit...
Synchronous insight of in vitro and in vivo biological activities of Sambucus n...
Mota, Ana Henriques; Andrade, Joana M.; Rodrigues, Maria Joao; Custódio, Luísa; Bronze, Maria Rosario; Duarte, Noelia; Baby, Andre; Rocha, JoaoThere is a re-emerging interest in natural products as reputable sources of new active pharmaceutical ingredients. This study synchronously reports in vitro, with more than one cell line, and in vivo biological activities of extracts obtained from Sambucus nigra. Using several solvents and techniques, eighteen extracts were obtained from fresh and dried berries, and fresh flowers. The flavonoid content and iden...
Zooming in with QSPR on Friedel-Crafts acylation reactions over modified BEA ze...
Aleixo, Odrigo; Elvas Leitao, Ruben; Martins, Filomena; Carvalho, Ana; Brigas, Amadeu Fernandes; Nunes, Ricardo; Fernandes, Auguste; Rocha, JoaoThe catalytic behaviour of hierarchical BEA zeolites with Si/Al ratio of 12.5 and 32 was studied in Friedel-Crafts acylation reactions using furan, anisole and pyrrole as substrates and acetic anhydride as acylating agent. Hierarchical BEA samples were submitted to alkaline and alkaline + acid treatments. Kinetic modelling using nonlinear regressions applied to a simplified Langmuir-Hinshelwood equation showed ...
Combination of hyaluronic acid and PLGA particles as hybrid systems for viscosu...
Mota, Ana Henriques; Direito, Rosa; Carrasco, Marta P.; Rijo, Patricia; Ascensao, Lia; Viana, Ana Silveira; Rocha, Joao; Eduardo-Figueira, MariaHyaluronic acid (HA) is commonly used through intra-articular administration for viscosupplementation in osteoarthritis and other disorders. HA is generally supplied as an injection commonly reported as painful, with strong limitations after treatment. In this study, an alternative delivery system was constructed based on HA hydrogel and poly(lactic-co-glycolic acid) (PLGA) particles with oleic acid. Developmen...
Zooming in with QSPR on Friedel-Crafts acylation reactions over modified BEA ze...
Aleixo, Odrigo; Elvas-Leitao, Ruben; Martins, Filomena; Carvalho, Ana P.; Brigas, Amadeu; Nunes, Ricardo; Fernandes, Auguste; Rocha, JoaoThe catalytic behaviour of hierarchical BEA zeolites with Si/Al ratio of 12.5 and 32 was studied in Friedel-Crafts acylation reactions using furan, anisole and pyrrole as substrates and acetic anhydride as acylating agent. Hierarchical BEA samples were submitted to alkaline and alkaline + acid treatments. Kinetic modelling using nonlinear regressions applied to a simplified Langmuir-Hinshelwood equation showed ...