43 documents found, page 1 of 5
Cefepime and amoxicillin increase metabolism and enhance caspofungin tolerance ...
Cordeiro, Rossana de Aguiar; Evangelista, Antonio Jose de Jesus; Serpa, Rosana; Andrade, Ana Raquel Colares de; Mendes, Patrícia Bruna LeiteIt is well known that prolonged antibiotic therapy alters the mucosal microbiota composition, increasing the risk of invasive fungal infection (IFI) in immunocompromised patients. The present study investigated the direct effect of b-lactam antibiotics cefepime (CEF) and amoxicillin (AMOX) on biofilm production by Candida albicans ATCC 10231. Antibacterials at the peak plasmatic concentration of each drug were ...
Effect of essential oils from Mangifera indica L. cultivars on the antifungal s...
Fontenelle, Raquel Oliveira dos Santos; Sobrinho, Antonio Carlos Nogueira; Soares, Bruna Vieira; Aguiar, Francisca Lidiane Linhares deThis work reports the chemical study, and anti- Candida spp. activity of leaf essential oil from Mangifera indica cultivars. The essential oils were obtained by hydro-distillation and analyzed by gas chromatography/mass spectroscopy. The anti- Candida spp. activity was evaluated against strains isolated from dogs by the agar-well diffusion method and the minimum inhibitory concentration (MIC) by the broth micro...
Tumor necrosis factor prevents Candida albicans biofilm formation
Rocha, Francisco Airton Castro; Alves, Anelise Maria Costa Vasconcelos; Rocha, Marcos Fábio Gadelha; Cordeiro, Rossana de Aguiar CordeiroCandida species are commensals but some develop biofilms in prosthetic materials and host surfaces that may represent up to 30% of deaths related to infections, particularly in immunosuppressed patients. Tumor necrosis factor (TNF) exhibits a plethora of functions in host defense mechanisms whereas excessive release of TNF in inflammation promotes tissue damage. Cytokines released in an inflammatory milieu may ...
Aeromonas and Plesiomonas species from scarlet ibis ( Eudocimus ruber ) and the...
Castelo-Branco, Débora Souza Collares Maia; Silva, Aline Lobão da; Monteiro, Frederico Ozanan Barros; Guedes, Glaucia Morgana de MeloThe present study aimed at evaluating the role of captive scarlet ibises (Eudocimus ruber) and their environment as reservoirs of Aeromonas spp. and Plesiomonas spp., and analyzing the in vitro antimicrobial susceptibility and virulence of the recovered bacterial isolates. Thus, non-lactose and weak-lactose fermenting, oxidase positive Gram-negative bacilli were recovered from cloacal samples (n = 30) of scarle...
Azole resistance in Candida albicans from animals: Highlights on efflux pump ac...
Rocha, Marcos Fábio Gadelha; Bandeira, Silviane Praciano; Alencar, Lucas Pereira de; Melo, Luciana Magalhães; Sales, Jamille AlencarThis study investigated potential mechanisms of azole resistance among Candida albicans from animals, including efflux pump activity, ergosterol content and gene expression. For this purpose, 30 azole-resistant C. albicans strains from animals were tested for their antifungal susceptibility, according to document M27-A3, efflux pump activity by rhodamine 6G test, ergosterol content and expression of the genes C...
Antiretroviral drugs saquinavir and ritonavir reduce inhibitory concentration v...
Brilhante, Raimunda Sâmia Nogueira; Caetano, Érica Pacheco; Riello, Giovanna Barbosa Riello; Guedes, Glaucia Morgana de MeloRecent studies have shown that some drugs that are not routinely used to treat fungalinfections have antifungal activity, such as protease inhibitor antiretroviral drugs. This studyinvestigated the in vitro susceptibility of Histoplasma capsulatum var. capsulatum to saquinavirand ritonavir, and its combination with the antifungal itraconazole. The susceptibility assaywas performed according to Clinical and Labo...
Antifungal resistance and virulence among Candida spp. from captive amazonian m...
Sidrim, José Júlio Costa; Carvalho, Vitor Luz; Castelo-Branco, Débora de Souza Collares Maia; Brilhante, Raimunda Sâmia NogueiraThis work aimed at evaluating the antifungal susceptibility and production of virulence factors by Candida spp. isolated from sirenians in Brazil. The isolates (n = 105) were recovered from the natural cavities of Amazonian and West Indian manatees and were tested for the susceptibility to amphotericin B, itraconazole, and fluconazole and for the production of phospholipases, proteases, and biofilm. The minimum...
Enterobacteria and Vibrio from Macrobrachium amazonicum prawn farming in Fortal...
Castelo-Branco, D ebora de Souza Collares Maia; Sales, Jamille Alencar; Brilhante, Raimunda Sâmia Nogueira; Guedes, Glaucia Morgana de MeloObjective: To investigate the isolation of enterobacteria associated with Macrobrachium amazonicum (M. amazonicum) farming and evaluate the in vitro antimicrobial susceptibility of Vibrio strains. Methods: Strains were isolated from female M. amazonicum prawns and environmental and hatchery water. Biochemical assays were used to identify bacterial genera and those belonging to the genus Vibrio were submitted to...
Vibrio spp. from Macrobrachium amazonicum prawn farming are inhibited by Moring...
Brilhante, Raimunda Sâmia Nogueira; Sales, Jamille Alencar; Sampaio, Celia Maria de Souza; Barbosa, Francisco Geraldo; Paiva, Manoel de Araújo NetoObjective To investigate the in vitro antimicrobial potential of extracts of stem, leaves, flowers, pods and seeds of Moringa oleifera (M. oleifera) against Vibrio spp. from hatchery water and the prawn Macrobrachium amazonicum. Methods The ethanol extracts of stem, leaves, pods and seeds and chloroform extract of flowers of M. oleifera were tested against Vibrio cholerae (V. cholerae) serogroups non-O1/non-O13...
In vitro inhibitory activity of terpenic derivatives against clinical and envir...
Brilhante, Raimunda Sâmia Nogueira; Marques, Natalya Fechine Silva; Castelo-Branco, Débora de Souza Collares Maia; Lima, Rita Amanda Chaves deSporotrichosis is a subacute or chronic subcutaneous infection, caused by the fungus Sporothrix schenkii complex, occurring in human and animal tissues. Potassium iodide and itraconazole have been used as effective therapy for first-choice treatment, while am- photericin B may be indicated for disseminated infection. However, the adverse effects of potassium iodide and amphotericin B or the long duration of the...