Tilapia skin has non-infectious microbiota, high amounts of type I collagen, and similar morphological structure to human skin, so it has been suggested as a potential xenograft for the management of burn wounds. A 23-year-old male patient, with no comorbidities, arrived at our burn treatment center after a thermal injury caused by contact with flames from a gunpowder explosion. Superficial partial thickness bu...
A obesidade infantil é um tema cada vez mais recorrente nos meios de saúde, pois se sabe que crianças obesas têm chances muito maiores de se tornarem um adulto obeso, assim, doenças relacionadas ao excesso de peso tenderão a aparecer de forma muito mais precoce, causando prejuÃzo à saúde dos indivÃduos. Este estudo objetivou avaliar a prevalência de sobrepeso e obesidade em crianças do ensino fundam...
Obesity and bariatric surgery may affect pharmacokinetic parameters that guarantee the success of a antibiotic therapeutic treatment. The objective of this study was to evaluate the impact of obesity and bariatric surgery on the pharmacokinetic parameters of amoxicillin. This was a randomized clinical trial, open-label, single-dose, with two periods of treatment in which participants (obese subjects who underwe...
The success of a therapeutic treatment depends upon the bioavailability of the drug, which can be influenced by food intake. This study aimed to evaluate the influence of food in the bioavailability of two formulations of venlafaxine administered at extended-release capsules in healthy volunteers. This open, randomized, crossover clinical trial was consisted of four periods, two sequences, in which healthy adul...