Encontrados 11 documentos, a visualizar página 1 de 2
Higher airborne pollen concentrations correlated with increased SARS-CoV-2 infe...
Damialis, Athanasios; Gilles, Stefanie; Sofiev, Mikhail; Sofieva, Viktoria; Kolek, Franziska; Bayr, Daniela; Plaza, Maria P.; Leier-irtz, VivienPollen exposure weakens the immunity against certain seasonal respiratory viruses by diminishing the antiviral interferon response. Here we investigate whether the same applies to the pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is sensitive to antiviral interferons, if infection waves coincide with high airborne pollen concentrations. Our original hypothesis was that more airbor...
Pollen and Spore Monitoring in the World. Clinical and Translational Allergy
Buters, Jeroen TM; Antunes, Célia M; Galveias, Ana; Bergmann, Karl C; Thibaudon, Michel; Galán, Carmen; Schmidt-Weber, Carsten; Oteros, JoseBackground Ambient air quality monitoring is a governmental duty that is widely carried out in order to detect non-biological (“chemical”) components in ambient air, such as particles of < 10 µm (PM10, PM2.5), ozone, sulphur dioxide, and nitrogen oxides. These monitoring networks are publicly funded and air quality data are open to the public. The situation for biological particles that have detrimental effects...
Cupressaceae pollen in the atmosphere of Alentejo: disruption of pollen grain d...
Antunes, Célia M; Galveias, Ana; Salgado, Rui; Bortoli, Daniele; Arriegas, Rute; Costa, Ana R; Costa, M JoãoBackground Cupressaceae family include several species that are widely used as ornamental plants pollinating in late winter - early spring, depending on the temperature. Despite being considered moderately allergenic, it might be responsible for winter allergic outbreaks. As ornamental trees, they are found scattered throughout the territory but are more abundant in pockets of wild forest, outside Alentejo. Des...
Association between Salivary Leptin Levels and Taste Perception in Children
Rodrigues, Lénia; Espanca, Rosa; Rodrigues Costa, Ana; Antunes, Célia M; Pomar, Clarinda; Capela e Silva, Fernando; Pinheiro, Cristina; Amado, FranciscoThe satiety inducing hormone leptin acts not only at central nervous system but also at peripheral level. Leptin receptors are found in several sense related organs, including the mouth. A role of leptin in sweet taste response has been suggested but, until now, studies have been based on in vitro experiments, or in assessing the levels of the hormone in circulation. The present study investigated whether the l...
Changes associated with Na,K-ATPase in brain, kidney, heart and liver of the sp...
Roque, Cátia; Costa, Ana R.; Capela-Silva, Fernando; Antunes, Célia MAlterations in Na,K-ATPase activity, in isoenzyme expression and/or number of units of the pump present in the plasma membrane have been associated with diabetes. These changes were described in different organs and tissues such as brain, heart, kidney, among others, and may result from altered insulin levels. However, the vast majority of studies were conducted in animal models of chemically induced diabetes, ...
Alterações na actividade enzimática da amílase salivar em indivíduos obesos
Simões, Carla; Costa, Ana Rodrigues; Antunes, Célia M; Lamy, ElsaNos últimos anos o estudo da composição proteica da saliva ganhou interesse pelo seu potencial no diagnóstico não invasivo e compreensão de diversas doenças, quer orais, quer sistémicas. Para além disso, a interacção deste fluido com os constituintes dos alimentos tornam a sua análise importante para a compreensão das variações a nível da percepção dos alimentos e escolhas alimentares. Há, contudo, poucos estud...
Differences in salivary α-amylase levels among women with different taste sensi...
Sequeira, Márcia; Rodrigues, Lénia; Costa, Ana R; Pinheiro, C; Antunes, Célia M; Lamy, ElsaSaliva is the main component of taste receptor cells external environment, and consequently it may have a decisive role in taste perception. Taste sensitivity varies among different individuals. Sensitivity to the compound n-6-propylthiouracil (PROP) has been considerably studied and besides the known influence of genetic background, the contribution of perireceptor environment is not completely clear yet. Sali...
Avaliação das alterações na sensibilidade para os gostos doce e amargo em ratos...
Pinheiro, Sandra; Rodrigues, Lenia; Costa, Ana R; Antunes, Célia M; Silva, Fernando C; Lamy, ElsaA obesidade é actualmente considerada uma epidemia estando associada a uma predisposição genética do indivíduo e a um consumo energético desadequado O consumo de alimentos ricos em gordura é um dos factores que contribui para o ganho de peso e obesidade. O gosto é um factor determinante na escolha de alimentos e variações individuais na sensibilidade gustativa podem condicionar os hábitos alimentares. O present...
Glucose-evoked Na+,K+-ATPase modulation in pancreatic ß-cells from normal and i...
Roque, Cátia; Costa, Ana R; Antunes, Célia MNa+,K+-ATPase is regulated by glucose in pancreatic ß-cells, a process that is altered in glucose impaired tolerance. Although AMP dependent protein kinase (AMPK), a metabolic sensor, is believed to be central in the signal transduction cascade underlying the Na+,K+-ATPase regulation in pancreatic β-cells, its role remains unknown. The aim of this work was to clarify the role of AMPK in glucoseevoked inhibition...
Avaliação e Caraterização da Ação Inibitória de Iminociclitóis na Atividade α-G...
Louro, Patricia R; Vannuchi, Nicholas; Carreiro, Elisabete P; Costa, Ana R; Burke, Anthony J; Antunes, Célia MA diabetes, em particular a diabetes mellitus tipo 2, constitui um distúrbio metabólico que se carateriza por glicemias aumentadas resultantes de diminuição da libertação e/ou ação da insulina. Os inibidores das α-glucosidases surgem como agentes de elevado interesse terapêutico uma vez que podem contribuir para a diminuição da absorção intestinal de glicose e, consequentemente, para um desagravamento da hiperg...