Clinical practice generates a wealth of data daily, collected for the purpose of providing healthcare. However, this data holds the potential to contribute to the generation of knowledge. The aim of this study was to describe the process of submitting requests for access to clinical records for research and the heterogeneity in the evaluation of a national research project by the boards of directors and ethics ...
The genus Orthoflavivirus includes several mosquito-borne pathogenic viruses, notably West Nile virus (WNV), which is endemic to the Mediterranean region. In Portugal, WNV circulation has been documented in equines, birds and mosquitoes, however human cases remain rare and no recent human seroprevalence studies have been conducted. This study aimed to estimate the national and regional seroprevalence of WNV amo...
Leishmania infantum, a zoonotic vector-born parasite, is endemic in the Mediterranean region, presenting mostly as visceral (VL), but also as cutaneous (CL) and mucosal leishmaniasis (ML). This study aimed to describe the epidemiological and clinical aspects of the CL and ML cases diagnosed in mainland Portugal between 2010 and 2020. Collaboration was requested from every hospital of the Portuguese National Hea...
Q fever (or query fever) is a zoonotic infectious disease with worldwide distribution transmitted by an intracellular Gram-negative bacterium, Coxiella burnetii. The most common identified sources of human infection are farm animals, such as sheep, goats and cattle. The disease is endemic in mainland Portugal, with most cases notified in the central and southern regions. Q fever is a complex and pleomorphic dis...
Objectives: To compare 7-year survival and freedom from reoperation, as well as early clinical and hemodynamic outcomes, after surgical aortic valve replacement (SAVR) with mechanical or bioprosthetic valves in patients aged 50-70 years. Methods: single-center retrospective cohort study including adults aged 50-70 years who underwent SAVR in 2012 with a mechanical or bioprosthetic valve. Median follow-up was 7 ...
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As eleições municipais de 2016 foram marcadas por um fenômeno conhecido como o “não voto”, ou seja, a rejeição e insatisfação aos candidatos e partidos políticos demonstradas na quantidade de votos em branco, nulo e abstenções. Apesar do quadro alarmante, os períodos eleitorais tendem a ter seus destaques. Isso porque candidatos sem viés ideológico claros, fora do sistema político tradicional e com forte discur...
The Event Handler – a publish-subscribe broker implemented over REST/HTTP(S) – is an auxiliary system of the Arrowhead framework for IoT applications. During this work we found that the existing implementation of the Event Handler suffers from serious performance issues. This paper describes the reengineering effort that ultimately enabled it to reach much more acceptable levels of performance, by using appropr...
The Arrowhead Framework, a SOA-based framework for IoT applications, provides the Event Handler system: a publish/subscribe broker implemented with REST/HTTP(S). However, the existing implementation of the Event Handler suffers from message latency problems that are not acceptable for industrial applications. Thus, this paper describes the refactoring process of this system that enabled it to reach acceptable l...
This communication describes research and development directions that are being explored for the creation of a maintenance system for home appliances. The solution will enable a faster and more accurate automation of after-sale services for home appliances. It will be based on three tiers: data acquisition, data analysis and business tiers. The communication provides a context for the work, both regarding the a...