INTRODUÇÃO. A Universidade é um espaço muito vislumbrado pelos jovens que concluem o ensino médio e que veem no ensino superior um horizonte a ser explorado com varias possibilidades. Para que eles conheçam suas opções e tenham uma familiaridade com a futura instituição, as ações de extensão são uma experiência concreta trazendo uma melhor percepção de quem e como se produz os conhecimentos. OBJETIVO. Com isso,...
Ethnopharmacological relevance: Triplaris gardneriana Wedd. (Polygonaceae family) is a plant species from Brazilian semiarid region which is used in local traditional medicine for the treatment of inflammatory condi tions such as hemorrhoids. Aim of the study: In this study, the in vitro anti-inflammatory activity of different concentrations of ethanolic extract from T. gardneriana seeds (EETg) was performed in...
Epiisopiloturine (EPI) is an imidazole alkaloid obtained from industrial waste generated by extracting pilocarpine from the leaves of Pilocarpus microphyllus, popularly known as jaborandi. Given the above, the aim of the present study was to investigate the effect of epiisopiloturine (EPI) and pharmaceutical formulation (EPI drops) in experimental models of acute and persistent nociception with description of t...
Contact dermatitis produces an inflammatory reaction primarily via stimulation of keratinocytes and cells of the immune system, which promote the release of cytokines, reactive oxygen species (ROS), and other chemical mediators. Eugenol (EUG, phenylpropanoid of essential oils) has attracted attention due to its anti-inflammatory properties, as well as antioxidant effect. On the other hand, it is volatile and in...
Medicinal plants have been shown to be promising as a source of alternative therapies to modulate the inflammatory response, including inflammatory pain. Pilocarpus microphyllus, popularly known as jaborandi, is a species native to the Northeast and widely exploited by the pharmochemical industry for the extraction of pilocarpine, a cholinergic imidazole alkaloid. Its leaves also have other alkaloids, such as e...