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Clinical correlates of social cognition after an ischemic stroke: preliminary f...
Souza,Maria de Fátima Dias de; Cardoso,Maíra Glória de Freitas; Vieira,Érica Leandro Marciano; Rocha,Natália Pessoa; Vieira,Talita Hélen Ferreira eABSTRACT. The co-occurrence of post-stroke behavioral disorders and cognitive impairment has been extensively investigated. However, studies usually do not include social cognition among the assessed cognitive domains. Objective: To investigate the potential association between facial emotion recognition, a measure of social cognition, and behavioral and cognitive symptoms in the subacute phase of ischemic stro...
Urinary cytokine profiles according to the site of blockade of the renin-angiot...
Baracho,Nilo César do Vale; Silveira,Kátia Daniela da; Rocha,Natália Pessoa; Cordeiro,Thiago Macedo; Feracin,Victor; Pereira,Regina MariaAbstract Introduction: It is still unknown how the pharmacological inhibition of the Renin Angiotensin System (RAS) impacts the levels of inflammation and fibrosis biomarkers. Objective: This study sought to evaluate the effect of enalapril, candesartan and aliskiren on urinary levels of cytokines in a model of chronic kidney disease (CKD). Methods: Male Wistar rats were submitted to surgical removal of ¾ of re...
Early changes in adipokines from overweight to obesity in children and adolescents
Mantovani,Rafael Machado; Rocha,Natália Pessoa; Magalhães,Daniel Massote; Barbosa,Izabela Guimarães; Teixeira,Antônio Lúcio; Silva,Ana Cristina Simões eAbstract Objective: Childhood obesity has been associated with metabolic syndrome and cardiovascular diseases. This study aimed to compare plasma levels of traditional metabolic markers, adipokines and soluble tumor necrosis factor receptor type 1 (sTNFR1) in overweight, obese and lean children. We also assessed the relationships of these molecules with classical metabolic risk factors. Methods: This study incl...
Characterization of an experimental model of progressive renal disease in rats
Baracho,Nilo César do Vale; Kangussu,Lucas Miranda; Prestes,Thiago Ruiz Rodrigues; Silveira,Kátia Daniela da; Pereira,Regina Maria; Rocha,Natália PessoaABSTRACT PURPOSE: To characterize an experimental model of progressive renal disease induced by different degrees of nephrectomy in rats. METHODS: Eighty male Wistar rats were divided into four experimental groups (n=20/group): sham surgery (control group), progressive degrees of nephrectomy leading to mild uremia (group 1), moderate uremia (group 2) and severe uremia (group 3). Ten animals of each group were f...
Persistent Sydenham’s chorea is not associated with sustained lymphocyte dysfun...
Torres,Karen Cecília de Lima; Rocha,Natália Pessoa; Rezende,Vítor Bortolo de; Dutra,Walderez Ornelas; Gollob,Kenneth John; Cardoso,FranciscoThe mechanisms involved in the symptoms of Sydenham’s chorea (SC) remain obscure. Taking into account the autoreactive antibody-mediated hypothesis of SC pathogenesis, the persistence of chorea may be associated with increased levels of B1 lymphocytes and other lymphocyte subsets. We evaluated lymphocyte subsets, including B1 and T cells, in patients with remitted (RSC) and persistent (PSC) SC by flow cytometry...
Frequency of overweight and obesity in children and adolescents with autism and...
Kummer,Arthur; Barbosa,Izabela Guimarães; Rodrigues,David Henrique; Rocha,Natália Pessoa; Rafael,Marianna da Silva; Pfeilsticker,LarissaAbstract Objective: To assess the frequency of overweight and obesity in children and adolescents with autism spectrum disorder (ASD) and with attention deficit/hyperactivity disorder (ADHD) and their parents, in comparison with children and adolescents without developmental disorders. Methods: Anthropometric measures were obtained in 69 outpatients with ASD (8.4±4.2 years old), 23 with ADHD (8.5±2.4) and 19 co...
Propriedades psicométricas da Escala de Responsividade Social-2 para Transtorno...
Barbosa,Izabela Guimarães; Rodrigues,David Henrique; Rocha,Natália Pessoa; Simões-e-Silva,Ana Cristina; Teixeira,Antônio Lúcio; Kummer,ArthurObjetivo O objetivo deste trabalho foi avaliar as propriedades psicométricas da versão em português da Escala de Responsividade Social-2 (ERS-2) para crianças e adolescentes com transtorno do espectro autista (TEA). Métodos A ERS-2 foi respondida pelos pais de 90 pacientes com TEA e 25 controles saudáveis. Análises quanto à validade discriminante, índices de confiabilidade e separação, de adequação e calibração...
Complexidade do regime terapêutico prescrito para idosos
Acurcio,Francisco de Assis; Silva,Anderson Lourenço da; Ribeiro,Andréia Queiroz; Rocha,Natália Pessoa; SilveIra,Micheline Rosa; Klein,Carlos HenriqueOBJETIVO: Analisar fatores associados à complexidade do esquema terapêutico em prescrições de medicamentos para idosos, em Belo Horizonte (MG). MÉTODOS: Inquérito domiciliar, com idosos selecionados por amostragem aleatória simples, a partir do cadastro do INSS. O Índice de Complexidade Terapêutica (ICT), medida direta das ações necessárias para administrar o medicamento, foi obtido de informações contidas na ú...