2 documents found, page 1 of 1
Tumor suppressor p53 protein expression : prognostic significance in patients w...
Duarte, Fernando Barroso; Gonçalves, Romelia Pinheiro; Barbosa, Maritza Cavalcante; Rocha Filho, Francisco Dário; Santos, Talyta Ellen de Jesus dosBackground: At the time of diagnosis, more than 50% of patients with myelodysplastic syn- drome have a normal karyotype and are classified as having a favorable prognosis. However, these patients often show very variable clinical outcomes. Furthermore, current diagnostic tools lack the ability to look at genetic factors beyond karyotyping in order to determine the cause of this variability. Objective: To evalua...
In vivo growth-inhibition of Sarc oma 180 tumor by alginates from brown seaweed...
Sousa, Alessandra Paula Alves de; Torres, Márcia Rocha; Pessoa, Cláudia; Moraes Filho, Manoel Odorico de; Rocha Filho, Francisco DárioPrevious studies had demonstrated that alginates from Sargassum sp. (Phaeophyta) showed a considerable activity against various murine tumors. The aim present study is to investigate the in vivo antitumor activity of two alginates (SVHV and SVLV) with di V erent viscosity extracted from brown seaweed Sargassum vulgare C. Agardh against Sarcoma 180 cells transplanted in mice. Both alginates inhibited growth of s...