3 documents found, page 1 of 1
Genetic Variants Are Not Rare in ICD Candidates with Dilated Cardiomyopathy: Ti...
Sousa, A; Canedo, P; Campelo, M; Moura, B; Leite, S; Baixia, M; Belo, A; Rocha-Gonçalves, F; Machado, JC; Silva-Cardoso, J; Martins, E; Investigators, FSudden cardiac death (SCD) risk stratification in dilated cardiomyopathy (DCM) has been based on left ventricular ejection fraction (LVEF), even though SCD may occur with LVEF > 35%. Family history of unexplained SCD, especially in the young, raises concern about potential inheritable risk factors. It remains largely unknown how genetic tests can be integrated into clinical practice, particularly in the selecti...
Direct, inflammation-mediated and blood-pressure-mediated effects of total and ...
Fontes-Carvalho, R; Gonçalves, A; Severo, M; Lourenço, P; Rocha-Gonçalves, F; Bettencourt, P; Leite-Moreira, A; Azevedo, ABackground: Obesity has been associated with subclinical diastolic dysfunction and increased risk of heart failure. Our aims were to evaluate the age- and sex-specific role of total and abdominal adiposity on diastolic function and to assess the direct and indirect pathophysiological mechanisms involved in this association. Methods and results: Within a population-based study (EPIPorto), a total of 1063 individ...
Left ventricular diastolic dysfunction and E/E ratio as the strongest echocardi...
Fontes-Carvalho, R; Sampaio, F; Teixeira, M; Rocha-Gonçalves, F; Gama, V; Azevedo, A; Leite-Moreira, ABackground The mechanisms that determine reduced exercise capacity after acute myocardial infarction (AMI) are not fully understood, especially the relative role of left ventricular diastolic and systolic function. Hypothesis To evaluate the role of different diastolic and systolic function echocardiographic parameters as predictors of reduced functional capacity in patients after AMI. Methods One month after A...