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Surgical site infection surveillance in knee and hip arthroplasty: optimizing a...

Guedes, M; Almeida, F; Andrade, P; Moreira, L; Pedrosa, A; Azevedo, A; Rocha-Pereira, N

Background: Surgical site infection (SSI) is an important cause of disease burden and healthcare costs. Fully manual surveillance is time-consuming and prone to subjectivity and inter-individual variability, which can be partly overcome by semi-automated surveillance. Algorithms used in orthopaedic SSI semi-automated surveillance have reported high sensitivity and important workload reduction. This study aimed ...


Contextual Hospital Conditions and the Risk of Nosocomial SARS-CoV-2 Infection:...

Almeida, F; Correia, S; Leal, C; Guedes, M; Duro, R; Andrade, P; Pedrosa, A; Rocha-Pereira, N; Lima-Alves, C; Azevedo, A

Objective: Knowledge of the role of hospital conditions in SARS-CoV-2 transmission should inform strategies for the prevention of nosocomial spread of this pathogen and of similarly transmitted viruses. This study aimed to identify risk factors for nosocomial acquisition of SARS-CoV-2. Methods: We ran a nested case-control study with incidence density sampling among adult patients hospitalized for >7 days (Augu...


Validation of a semi-automated surveillance system for surgical site infections...

Malheiro, R; Rocha-Pereira, N; Duro, R; Pereira, C; Alves, CL; Correia, S

Objectives. To assess whether electronic records data could improve the efficiency, exhaustiveness, and representativeness of SSI surveillance by selecting a group of high-risk patients for manual review. Methods. Colorectal surgeries (2016–2018) and cholecystectomies (2017–2018) were selected. Post-surgical antibiotic use, positive culture, C-reactive protein (CRP) values, body temperature, leukocyte count, su...


Persuasive antimicrobial stewardship intervention in the context of a KPC outbr...

Rocha-Pereira, N; Figueiredo Dias, P; Correia, S; Shahriari, S; Neves, J; Teixeira, J; Paiva, JA; Lima Alves, C; Azevedo, A

Introduction. Antimicrobial resistance is a major public health threat. Antimicrobial stewardship (AMS) is one of the key strategies to overcome resistance, but robust evidence on the effect of specific interventions is lacking. We report an interrupted time series (ITS) analysis of a persuasive AMS intervention implemented during a KPC producing Klebsiella pneumoniae outbreak. Methods. A controlled ITS for car...


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