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The impact of an 8-week Pilates-based physical training program on functional m...

Lima, M; Silva, B; Rocha-Rodrigues, S; Bezerra, P

Study aim: This study aimed to evaluate the effects of a Pilates-based training program on functional mobility and strength in community-dwelling adults over 70 years old. Material and methods: Twenty community-dwelling elderly subjects were recruited and randomly assigned to control (C = 10) or Pilates training (PT = 10) groups for 8 weeks (2 times/week). Anthropometric, strength, cardiorespiratory fitness, fu...


Bidirectional interactions between the menstrual cycle, exercise training, and ...

Rocha-Rodrigues, S; Sousa, M; Reis, PL; Leão, C; Cardoso-Marinho, B; Massada, M; Afonso, J

Women have a number of specificities that differentiate them from men. In particular, the role of sex steroid hormones and the menstrual cycle (MC) significantly impact women’s physiology. The literature has shown nonlinear relationships between MC, exercise, and nutritional intake. Notably, these relationships are bidirectional and less straightforward than one would suppose. For example, the theoretical impli...


Strength training to prevent falls in older adults: A systematic review with me...

Claudino, JG; Afonso, J; Sarvestan, J; Lanza, MB; Pennone, J; Filho, CAC; Serrão, JC; Espregueira-Mendes, J; Vasconcelos, ALV; Andrade, MP

We performed a systematic review with meta-analysis of randomized controlled trials (RCTs) to assess the effects of strength training (ST), as compared to alternative multimodal or unimodal exercise programs, on the number of falls in older adults (=60 years). Ten databases were consulted (CINAHL, Cochrane Library, EBSCO, EMBASE, PEDro, PubMed, Scielo, Scopus, SPORTDiscus and Web of Science), without limitation...


Skeletal muscle–adipose tissue–tumor axis: Molecular mechanisms linking exercis...

Rocha-Rodrigues, S; Matos, M; Afonso, J; Mendes-Ferreira, M; Abade, E; Teixeira, E; Silva, B; Murawska-Cialowicz, E; Oliveira, MJ; Ribeiro, R

Increased visceral adiposity may influence the development of prostate cancer (PCa) aggressive tumors and cancer mortality. White adipose tissue (WAT), usually referred to as periprostatic adipose tissue (PPAT), surrounds the prostatic gland and has emerged as a potential mediator of the tumor microenvironment. Exercise training (ET) induces several adaptations in both skeletal muscle and WAT. Some of these eff...


Bdnf impact on biological markers of depression—role of physical exercise and t...

Murawska-Cialowicz, E; Wiatr, M; Cialowicz, M; Assis, GG; Borowicz, W; Rocha-Rodrigues, S; Paprocka-Borowicz, M; Marques, A

Depression is the most common and devastating psychiatric disorder in the world. Its symptoms, especially during the pandemic, are observed in all age groups. Exercise training (ET) is well known as a non-pharmacological strategy to alleviate clinical depression. The brain-derived neurotrophic factor (BDNF) is one of the biological factors whose expression and secretion are intensified in response to ET. BDNF i...


The Hamstrings: Anatomic and Physiologic Variations and Their Potential Relatio...

Afonso, J; Rocha-Rodrigues, S; Clemente, FM; Aquino, M; Nikolaidis, PT; Sarmento, H; Fílter, A; Olivares-Jabalera, J; Ramirez-Campillo, R

The incidence and recurrence of hamstrings injuries are very high in sports, posing elevated performance and financial-related costs. Attempts to identify the risk factors involved in predicting vulnerability to hamstrings injury is important for designing exercise-based programs that aim to mitigate the rate and severity of hamstrings injuries and improve rehabilitation strategies. However, research has shown ...


Browning of white adipocytes: melanocortins as essential players

Salazar, M J; Rodrigues, A R; Rocha-Rodrigues, S; Goncalves, I O; Almeida, H; Magalhaes, J; Gouveia, Alexandra


Role of physical exercise on hepatic insulin, glucocorticoid and inflammatory s...

Passos, E; Pereira, CD; Gonçalves, IO; Rocha-Rodrigues, S; Silva, N; Guimarães, JT; Neves, D; Ascensão, A; Magalhães, J; Martins, MJ

Aims Pro-inflammatory mediators, glucocorticoids and transforming growth factor (TGF)-β are implicated in the pathogenesis of non-alcoholic steatohepatitis (NASH)-related insulin resistance. As physical activity is beneficial against NASH, we analyzed the voluntary physical activity (VPA) and endurance training (ET) (preventive and therapeutic strategies) effects on hepatic insulin, pro-inflammatory and glucoco...


Exercise mitigates diclofenac-induced liver mitochondrial dysfunction

Santos-Alves, E; Marques-Aleixo, I; Coxito, P; Balça, MM; Rizo-Roca, D; Rocha-Rodrigues, S; Martins, S; Torrella, JR; Oliveira, PJ; Moreno, AJ

Background: Several strategies have been developed to counteract liver injury as a consequence of nonsteroid anti-inflammatory drugs toxicity. Here, we aimed to determine whether physical exercise results in liver mitochondrial protection against in vitro diclofenac toxicity. Material and methods: Male adult Sprague-Dawley rats were divided into sedentary, 12-week endurance training (ET) and voluntary activity ...


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