3 documents found, page 1 of 1
Principles in the Management of Glioblastoma
Roda, Domingos; Veiga, Pedro; Melo, Joana Barbosa; Carreira, Isabel Marques; Ribeiro, Ilda PatríciaGlioblastoma, the most aggressive and common malignant primary brain tumour, is characterized by infiltrative growth, abundant vascularization, and aggressive clinical evolution. Patients with glioblastoma often face poor prognoses, with a median survival of approximately 15 months. Technological progress and the subsequent improvement in understanding the pathophysiology of these tumours have not translated in...
RADIATION-ASSOCIATED CUTANEOUS BREAST ANGIOSARCOMA – 12 YEARS ANALYSIS OF A RAD...
Roda, Domingos; Melo, Gilberto; Figueiredo, PauloIntroduction: The radiation induced (RI) cutaneous angiosarcoma (CAS) in the context of the treatment of breast cancer is a rare but extremely aggressive tumor.Aim: The aim of this study was to review and present the clinical cases of RI CAS of a Radiotherapy (RT) service of, by analyzing the clinical in the last 12 years.Material and Methods: We retrospectively analyzed the clinical cases of primary atypical v...
Secondary Hypothyroidism after Cervical Irradiation: Systematic Evaluation of T...
Gonçalves, Sara Monteiro; Ferreira, Brigida da Costa; Guardado, Maria João; Marques, Rui; Serra, Tânia; Serra, Maria João; Roda, DomingosIntroduction: Sometimes Thyroid dysfunction is an underestimated consequence of radiation exposure. The underlying mechanism is not clearly understood, but it is likely to be multifactorial. As so, the specific risk factors associated with the development of secondary radiotherapy hypothyroidism remain undefined. The direct irradiation of the thyroid gland may result more frequently in hypothyroidism. This is a...