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Senile Systemic Amyloidosis: An Underdiagnosed Disease.

Manso, M; Marques, D; Rocha, S; Rodeia, S; Domingos, R

Senile systemic amyloidosis is caused by a non-mutated form of transthyretin with the heart being the major organ involved. This infiltrative cardiomyopathy usually presents as slowly progressive heart failure. An 82-year-old female patient was admitted for newly diagnosed heart failure. A year later she presented with decompensated heart failure and syncope. Inpatient work-up showed persistently elevated tropo...


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