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Mastocytosis presenting with mast cell-mediator release-associated symptoms eli...

Rama, TA; Morgado, JM; Henriques, A; Escribano, L; Alvarez-Twose, I; Sanchez-Muñoz, L; Moreira, A; Romão, J; Órfão, A; Matito, A

Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently avoided in mastocytosis, because of a potential increased risk for drug hypersensitivity reactions (DHRs) due to inhibition of cyclo-oxygenase (COX), subsequent depletion of prostaglandin E2 and release of leukotrienes. Objectives: Here, we aimed at determining the prevalence of mast cell (MC) mediator release symptoms triggered by NSAIDs ...

Date: 2022   |   Origin: Repositório Aberto da Universidade do Porto
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