2 documents found, page 1 of 1
Apoe variants in an iberian alzheimer cohort detected through an optimized sang...
González, RD; Gomes, I; Gomes, C; Rocha, R; Durães, L; Sousa, P; Figueruelo, M; Rodríguez, M; Pita, C; Hornero, R; Gómez, C; Lopes, AM; Pinto, NThe primary genetic risk factor for late onset Alzheimer’s disease (LOAD) is the APOE4 allele of Apolipoprotein E (APOE) gene. The three most common variants of APOE are determined by single nucleotide polymorphisms (SNPs) rs429358 and rs7412. Our aim was to estimate allele and genotype frequencies of APOE variants in an Iberian cohort, thus helping to understand differences in APOE-related LOAD risk observed a...
Genome-wide scan for five brain oscillatory phenotypes identifies a new qtl ass...
Rebelo, MÂ; Gómez, C; Gomes, I; Poza, J; Martins, S; Maturana-Candelas, A; Ruiz-Gómez, SJ; Durães, L; Sousa, P; Figueruelo, M; Rodríguez, M; Pita, CBrain waves, measured by electroencephalography (EEG), are a powerful tool in the investigation of neurophysiological traits and a noninvasive and cost-effective alternative in the diagnostic of some neurological diseases. In order to identify novel Quantitative Trait Loci (QTLs) for brain wave relative power (RP), we collected resting state EEG data in five frequency bands (d, ¿, a, ß1, and ß2) and genome-wide...