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Salivary Leucocytes as In Vitro Model to Evaluate Nanoparticle-Induced DNA Damage

Valdiglesias, Vanessa; Fernández-Bertólez, Natalia; Lema-Arranz, Carlota; Rodríguez-Fernández, Raquel; Pásaro, Eduardo; Reis, Ana Teresa

Metal oxide nanoparticles (NPs) have a wide variety of applications in many consumer products and biomedical practices. As a result, human exposure to these nanomaterials is highly frequent, becoming an issue of concern to public health. Recently, human salivary leucocytes have been proposed as an adequate non-invasive alternative to peripheral blood leucocytes to evaluate genotoxicity in vitro. The present stu...

Date: 2021   |   Origin: Repositório Científico do Instituto Nacional de Saúde
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