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The neurobiological hypothesis of neurotrophins in the pathophysiology of schiz...

Rodrigues-Amorim, Daniela; Rivera-Baltanás, Tania; Peixoto, João Miguel Seiça Bessa; Sousa, Nuno; Vallejo-Curto, María de Carmen

Schizophrenia is associated with patterns of aberrant neurobiological circuitry. The disease complexity is mirrored by multiple biological interactions known to contribute to the disease pathology. One potential contributor is the family of neurotrophins which are proteins involved in multiple functional processes in the nervous system, with crucial roles in neurodevelopment, synaptogenesis and neuroplasticity....


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