6 documents found, page 1 of 1
Crohn disease with unusual cutaneous expression.
Soares, R O; Rebocho, L; Leitão, J; Freitas, J P; Lucas, M; Marques, A; Batista, A; Paredes, F; Garcia e Silva, L; Rodrigo, F GPerianal fistula is a frequent complication of Crohn's disease. The diagnosis of the later may be difficult if cutaneous disease is dominant, and sometimes an important clinical challenge. The authors report a case of a 34 year old male complaining of painful perianal nodules for the three last years. Cutaneous histopathological examination was inespecific and colonoscopy normal. Pelvic CT scan and fistulograph...
Dermatitis artefacta.
Reis, M D; Barbosa, A; Matildes, J; Freitas, J P; Rodrigo, F GWe report a case of a 29-year-old man presenting skin ulcerations on both sides of the mandible. The diagnosis of dermatitis artefacta was based on the morphology and evolution of the lesions, on the patient's borderline personality, on the objects found in his possession, and a later admission of having an involvement in the aggravation of the lesions.; We report a case of a 29-year-old man presenting skin ulc...
Fluorescent products in the crystalline lens of type ii diabetic patients.
Silva, J; Freitas, J P; Filipe, P; Vendrell, E; Rodrigo, F GA body of evidence suggests that glycation of proteins and the resulting fluorescent products take part in the late complications of diabetes. The purpose of this study was to analyse the fluorescence of lens soluble proteins from diabetic patients. Soluble proteins were obtained from lens with cataract from 20 type II diabetic patients and from 21 non diabetic controls with similar age. The fluorescence of the...
Malignant melanoma. A current problem.
Rodrigo, F G; Correia, M PMalignant Melanoma is a tumor of high malignancy which incidence has been shown to increase dramatically during last decades. The genesis of the tumor is uncertain, however the cutaneous fair complexion, the number and type of pigmented nevei and acute intermittent sun exposure with sunburn may play a significant role in its development. Histopathology of suspicious lesions is obligatory as diagnostic proof and...
Epidermolysis bullosa and dermo-epidermic junction. Clinico-pathologic correlat...
Rodrigo, F G; Mayer-da-Silva, A JEpidermolysis bullosa encompasses a group of hereditary diseases clinically and pathologically characteristic. In this review the grouping criteria commonly accepted for their classification are described. The cleavage phenomena observed in these diseases are analysed in accordance with the concept of a skin area including dermal and epidermal interrelated structures--the dermo-epidermal junction zone. Finally ...
Skin aging. Physiopathology and clinical perspective.
Rodrigo, F G; Mayer-da-Silva, A J; Freitas, J PThe main structural and functional alterations observed during skin ageing are reviewed, considering the intrinsic process of senescence and the damage induced by chronic exposure to actinic radiation. In photo-ageing the importance of skin type is stressed, concerning its capacity to tan in order to get protection against radiation. Finally some inflammatory, degenerative and neoplastic skin diseases associate...