2 documents found, page 1 of 1
Menthol and menthone associated with acetylsalicylic acid and their relation to...
Feitosa, Karina A.; Zaia, Maurício G.; Rodrigues, Vanderlei; Castro, Cynthia A.; Correia, Ricardo de O.; Pinto, Fábio G.; Rossi, Karina N.Z.P.Schistosomiasis is an important parasitic disease caused by Schistosoma mansoni, an intravascular trematode. Schistosomiasis treatment is limited to just one drug, Praziquantel (PZQ). Thus, studies on new antischistosomal compounds are of fundamental importance to disease control. Here we report on the effects of Mentha piperita L. compounds - menthol and menthone - in association with acetylsalicylic acid (ASA...
Curcumin generates oxidative stress and induces apoptosis in adult schistosoma ...
De Aguiar, Daniela Paula; Moscardini, Mayara Brunetto Moreira; Morais, Enyara Rezende; De Paula, Renato Graciano; Ferreira, Pedro Manuel; Afonso, AnaInducing apoptosis is an interesting therapeutic approach to develop drugs that act against helminthic parasites. Researchers have investigated how curcumin (CUR), a biologically active compound extracted from rhizomes of Curcuma longa, affects Schistosoma mansoni and several cancer cell lines. This study evaluates how CUR influences the induction of apoptosis and oxidative stress in couples of adult S. mansoni...