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Maternal heart exhibits metabolic and redox adaptations post-uncomplicated preg...

Tocantins, Carolina; Martins, João D.; Rodrigues, Óscar M; Grilo, Luís F.; Diniz, Mariana S.; Stevanovic-Silva, Jelena; Beleza, Jorge; Coxito, Pedro

Pregnancy may be a challenging period for the maternal systems and has been regarded as a stress test, as imperceptible/mild dysfunctions eventually present may be exacerbated during this period. The cardiovascular system is no exception, and several morphological and functional adaptations accompanying pregnancy have been described. However, long-term pregnancy-induced cardiac molecular alterations remain high...


Metabolic mitochondrial alterations prevail in the female rat heart 8 weeks aft...

Tocantins, Carolina; Martins, João D; Rodrigues, Óscar M; Grilo, Luís F; Diniz, Mariana S.; Stevanovic-Silva, Jelena; Beleza, Jorge; Coxito, Pedro

The consumption of high-caloric diets strongly contributes to the development of non-communicable diseases (NCDs), including cardiovascular disease, the leading cause of mortality worldwide. Exercise (along with diet intervention) is one of the primary non-pharmacological approaches to promote a healthier lifestyle and counteract the rampant prevalence of NCDs. The present study evaluated the effects of exercis...


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