9 documents found, page 1 of 1
COPD as a COVID-19 risk group: is genetic background the reason?
Marçalo, R.; Neto, S.; Pinheiro, M.; Rodrigues, A. J.; Sousa, N.; Santos, M. A. S.; Simão, P.; Valente, C.; Andrade, L.; Marques, A.; Moura, G. R.People with chronic obstructive pulmonary disease (COPD) constitute one of COVID-19 risk groups for poor prognosis upon infection. Variability in predisposition and clinical response to COVID-19 exist but our understanding of these factors in the COPD population is limited. This study explored the genetic background as a possible answer to COVID-19 infection response heterogeneity, either for the poor prognosis...
Deciphering COPD as a risk group for COVID-19: can we blame genetics?
Marçalo, R.; Neto, S.; Pinheiro, M.; Rodrigues, A. J.; Sousa, N.; Santos, M. A. S.; Simão, P.; Valente, C.; Andrade, L.; Marques, A.; Moura, G. R.People with chronic obstructive pulmonary disease (COPD) constitute one of COVID-19 risk groups. Variability in predisposition and clinical response to COVID-19 exist but our understanding of these factors in the COPD population is limited. This study explored the genetic background as a possible answer to COVID-19 infection response heterogeneity, either for the poor prognosis in people with COPD or across wor...
Genetic risk for COVID-19 outcomes in COPD and differences among worldwide popu...
Marçalo, R.; Neto, S.; Pinheiro, M.; Rodrigues, A. J.; Sousa, N.; Santos, M. A. S.; Simão, P.; Valente, C.; Andrade, L.; Marques, A.; Moura, G. R.People with chronic obstructive pulmonary disease (COPD) constitute one of COVID-19 risk groups for poor prognosis upon infection. Variability in predisposition and clinical response to COVID-19 exist but our understanding of these factors in the COPD population is limited. This study explored the genetic background as a possible answer to COVID-19 infection response heterogeneity, either for the poor prognosis...
Association of positive and negative life events with cognitive performance and...
Castanho, T. C.; Santos, N. C.; Meleiro-Neves, C.; Neto, S.; Moura, G. R.; Santos, M.; Cruz, A.R.; Cunha, O.; Castro Rodrigues, A.; Rodrigues, A. J.Objectives: Life events have important effects on psychological well-being. Yet, studies have mainly focused on exploring the impact of traumatic and negative experiences on health and well-being, with positive events receiving marginal attention. In this study, we investigated the association between negative and positive life events, cognitive performance and psychological status in older individuals. Method:...
Tau-dependent suppression of adult neurogenesis in the stressed hippocampus
Dioli, Chrysoula; Patrício, P.; Trindade, R.; Pinto, L. G.; Silva, J. M.; Morais, M.; Ferreiro, E.; Borges, S.; Mateus-Pinheiro, A.; Rodrigues, A. J.Stress, a well-known sculptor of brain plasticity, is shown to suppress hippocampal neurogenesis in the adult brain; yet, the underlying cellular mechanisms are poorly investigated. Previous studies have shown that chronic stress triggers hyperphosphorylation and accumulation of the cytoskeletal protein Tau, a process that may impair the cytoskeleton-regulating role (s) of this protein with impact on neuronal f...
Influência da profundidade e posição de semeadura na emergência de Acacia polyp...
Rodrigues, A. J.; Batista, E. M. C.; Oliveira, L. M.; Portella, A. C. F.; Souza, P. B.A Acacia polyphylla DC. é uma leguminosa, pertencente à família Fabaceae, conhecida principalmente por monjoleiro, cuja árvore apresenta porte médio e rápido crescimento, a mesma enquadra-se em estágios iniciais da sucessão secundária com grande potencial para o uso na recuperação de áreas degradadas do Bioma Cerrado. Assim, objetivou-se avaliar a influência de diferentes posições e de profundidades de semeadur...
Unveiling the effects of the secretome of mesenchymal progenitors from the umbi...
Fraga, J. S.; Silva, N. A.; Lourenço, A. S.; Gonçalves, V.; Neves, N. M.; Reis, R. L.; Rodrigues, A. J.; Manadas, B.; Sousa, N.; Salgado, A. J.It has been previously shown that the secretome of Human Umbilical Cord Perivascular Cells (HUCPVCs), known for their mesenchymal like stem cell character, is able to increase the metabolic viability and hippocampal neuronal cell densities. However, due to the different micro-environments of the distinct brain regions it is important to study if neurons isolated from different areas have similar, or opposite, r...
Unveiling the effects of the secretome of mesenchymal progenitors from the umbi...
Fraga, J. S.; Silva, N. A.; Lourenço, A. S.; Gonçalves, V.; Neves, N. M.; Reis, R. L.; Rodrigues, A. J.; Manadas, B.; Sousa, N.; Salgado, A. J.It has been previously shown that the secretome of Human Umbilical Cord Perivascular Cells (HUCPVCs), known for their mesenchymal like stem cell character, is able to increase the metabolic viability and hippocampal neuronal cell densities. However, due to the different micro-environments of the distinct brain regions it is important to study if neurons isolated from different areas have similar, or opposite, r...
Phase error resilience to I/Q mismatch of a simplified CPM receiver
Monteiro, F. A.; Rodrigues, A. J.A low complexity receiver which was devised in previous papers proved there to be quasioptimum over additive gaussian noise and also showed low power penalty with flat Rayleigh fading, i.e., with random phase, and despite the fact that one of three reduced complexity blocks of that receiver relies on symmetries on signal's phase transitions. This letter analyzes the origin of that error resilience during the de...