22 documents found, page 1 of 3
Peptide-keratin interactions for enhanced hair properties
Carvalho, José; Rodrigues, Ana Rita O.; Ferreira, Tiago; Gomes, Vânia; Pereira, Francisco; Martins, Cátia D. F.; Martins, MadalenaSummary Fusion peptides inspired by natural elastomeric proteins are fused to a keratin peptide (KP) and tested on damaged hair. Here, we report thermal and mechanical tests conducted on treated damaged hair in conjunction with the peptides physicochemical properties, resulting in a statistical multiparametric analysis. Among the parameters, the Youngs modulus and the keratin helix denaturation temperature show...
Self-assembly of Boc-p-nitro-l-phenylalanyl-p-nitro-l-phenylalanine and Boc-l-p...
Baptista, Rosa Maria Ferreira; Lopes, Paulo Estevão Caldeira; Rodrigues, Ana Rita O.; Cerca, Nuno; Belsley, M.; de Matos Gomes, EtelvinaSelf-assembly of two N-tert-butoxycarbonyl (Boc) protected analogues of diphenylalanine dipeptide, Boc-p-nitro-l-phenylalanyl-p-nitro-l-phenylalanine and Boc-l-phenylalanyl-l-tyrosine, respectively, Boc-pNPhepNPhe and Boc-PheTyr, in 1,1,1,3,3,3-hexafluoro-2-propanol/ethanol(water) solvents and into electrospun fibers is studied. Uncommon dual self-assembly is found for Boc-pNPhepNPhe, with the formation of nano...
Synthesis, computational and nanoencapsulation studies on eugenol-derived insec...
Coelho, Catarina M. M.; Pereira, Renato B.; Vieira, Tatiana F.; Teixeira, Cláudia M.; Fernandes, Maria José Gomes; Rodrigues, Ana Rita O.A new set of alkoxy alcohols were synthesised by reaction of eugenol oxirane with aliphatic and aromatic alcohols. These eugenol derivatives were evaluated against their effect upon the viability of the insect cell line Sf9 (Spodoptera frugiperda). The most promising compounds, 4-(3-(tert-butoxy)-2-hydroxypropyl)-2-methoxyphenol and 4-(2-((4-fluorobenzyl)oxy)-3-hydroxypropyl)-2-methoxyphenol were submitted to i...
Magnetoliposomes based on magnetic/plasmonic nanoparticles loaded with tricycli...
Rio, Irina S.R.; Rodrigues, Ana Rita O.; Rodrigues, Juliana M.; Queiroz, Maria João R.P.; Calhelha, Ricardo C.; Ferreira, Isabel C.F.R.Liposome-like nanoarchitectures containing manganese ferrite nanoparticles covered or decorated with gold were developed for application in dual cancer therapy, combining chemotherapy and photothermia. The magnetic/plasmonic nanoparticles were characterized using XRD, UV/Visible absorption, HR-TEM, and SQUID, exhibiting superparamagnetic behavior at room temperature. The average size of the gold-decorated nanop...
Development of novel magnetoliposomes containing nickel ferrite nanoparticles c...
Rio, Irina S. R.; Rodrigues, Ana Rita O.; Rodrigues, Carolina P.; Almeida, B. G.; Pires, A.; Pereira, A. M.; Araújo, J. P.; Castanheira, Elisabete M. S.Multifunctional nanosystems combining magnetic and plasmonic properties are a promising approach for cancer therapy, allowing magnetic guidance and a local temperature increase. This capability can provide a triggered drug release and synergistic cytotoxic effect in cancer cells. In this work, nickel ferrite/gold nanoparticles were developed, including nickel ferrite magnetic nanoparticles decorated with plasmo...
Magnetoliposomes containing calcium ferrite nanoparticles for applications in b...
Pereira, Daniela S.M.; Cardoso, Beatriz D.; Rodrigues, Ana Rita O.; Amorim, Carlos O.; Amaral, Vítor S.; Almeida, Bernardo G.; Queiroz, Maria João R.P.Magnetoliposomes containing calcium ferrite (CaFe2O4) nanoparticles were developed and characterized for the first time. CaFe2O4 nanoparticles were covered by a lipid bilayer or entrapped in liposomes forming, respectively, solid or aqueous magnetoliposomes as nanocarriers for new antitumor drugs. The magnetic nanoparticles were characterized by UV/Visible absorption, XRD, HR-TEM, and SQUID, exhibiting sizes of...
Magnetoliposomes containing calcium ferrite nanoparticles for applications in b...
Pereira, Daniela S. M.; Cardoso, Beatriz D.; Rodrigues, Ana Rita O.; Amorim, Carlos O.; Amaral, Vítor S.; Almeida, B. G.; Queiroz, Maria João R. P.Magnetoliposomes containing calcium ferrite (CaFe<sub>2</sub>O<sub>4</sub>) nanoparticles were developed and characterized for the first time. CaFe<sub>2</sub>O<sub>4 </sub>nanoparticles were covered by a lipid bilayer or entrapped in liposomes forming, respectively, solid or aqueous magnetoliposomes as nanocarriers for new antitumor drugs. The magnetic nanoparticles were characterized by UV/Visible absorption,...
Magnetoliposomes as carriers for promising antitumor thieno[3,2-b]pyridin-7-ary...
Rodrigues, Ana Rita O.; Almeida, Bernardo G.; Rodrigues, Juliana M.; Queiroz, Maria João R.P.; Calhelha, Ricardo C.; Ferreira, Isabel C.F.R.; Pires, A.Magnetoliposomes containing superparamagnetic manganese ferrite nanoparticles were tested as nanocarriers for two new promising antitumor drugs, a N-(3-methoxyphenyl)thieno[3,2-b]pyridin-7-amine (1) and a N-(2-methoxy-phenyl)thieno[3,2-b] pyridin-7-amine (2). The fluorescence emission of both compounds was studied in different polar and non-polar media, evidencing a strong intramolecular charge transfer charact...
Magnetoliposomes as carriers for promising antitumor thieno[3,2-b]pyridin-7-ary...
Rodrigues, Ana Rita O.; Almeida, B. G.; Rodrigues, Juliana M.; Queiroz, Maria João R. P.; Calhelha, Ricardo C.; Ferreira, Isabel C. F. R.; Pires, A.Magnetoliposomes containing superparamagnetic manganese ferrite nanoparticles were tested as nanocarriers for two new promising antitumor drugs, a N-(3-methoxyphenyl)thieno[3,2-b]pyridin-7-amine (1) and a N-(2-methoxy-phenyl)thieno[3,2-b]pyridin-7-amine (2). The fluorescence emission of both compounds was studied in different polar and non-polar media, evidencing a strong intramolecular charge transfer characte...
Magnetic Liposomes based on Nickel Ferrite Nanoparticles for biomedical applica...
Rodrigues, Ana Rita O.; Gomes, I. Tarroso; Almeida, B. G.; Araújo, João P.; Castanheira, Elisabete M. S.; Coutinho, Paulo J. G.Nickel ferrite nanoparticles with superparamagnetic behavior at room temperature were synthesized by a coprecipitation method. These magnetic nanoparticles were either covered with a lipid bilayer, forming dry magnetic liposomes (DMLs), or entrapped in liposomes, originating aqueous magnetoliposomes (AMLs). A new and promising method for the synthesis of DMLs is described. The presence of the lipid bilayer in D...