Os aeroportos ocupam um lugar central nas redes de transporte, conectando as regiões à economia mundial e possibilitando o fluxo de pessoas, bens, serviços e informações. As infraestruturas aeroportuárias são essenciais para a estratégia de desenvolvimento económico dos países, sobretudo dos mais periféricos como Portugal, permitindo mitigar ou ultrapassar os efeitos negativos das longas distâncias aos principa...
High-fat diet has been associated with a chronic-low grade inflammation in both adipose tissue and central nervous system. Fatty acids are known to cross the blood-brain barrier and reach the central nervous system where they can accumulate. Microglia express a wide range of lipid-sensitive receptors, potentially triggering inflammatory responses. Since fatty acids can exert pro and anti-inflammatory effects in...
We develop a real options model that examines the effect of government's subsidies and taxation policy on the timing and size of investments. We find that a higher depreciation rate or subsidy, or a lower tax rate, accelerates investments. The effect of subsidies on the investment size depends on whether the subsidy is fixed or variable: a fixed subsidy induces smaller size investments, whereas a variable subsi...
Nervous tissue homeostasis requires the regulation of microglia activity. Using conditional gene targeting in mice, we demonstrate that genetic ablation of the small GTPase Rhoa in adult microglia is sufficient to trigger spontaneous microglia activation, producing a neurological phenotype (including synapse and neuron loss, impairment of long-term potentiation [LTP], formation of β-amyloid plaques, and memory ...
This paper presents a novel analysis of two feed-in tariffs (FIT) under market and regulatory uncertainty, namely a sliding premium with cap and floor and a minimum price guarantee. Regulatory uncertainty is modeled with a Poisson process, whereby a jump event may reduce the tariff before the signature of the contract. Using a semi-analytical real options framework, we derive the project value, the optimal inve...
This paper presents a novel analysis of two feed-in tariffs (FIT) under market and regulatory uncertainty, namely a sliding premium with cap and floor and a minimum price guarantee. Regulatory uncertainty is modeled with a Poisson process, whereby a jump event may reduce the tariff before the signature of the contract. Using a semi-analytical real options framework, we derive the project value, the optimal inve...
This paper presents a novel model to analyze the effects on the investment timing and social welfare of three feed-in tariffs (FIT) within an oligopolistic market structure. The FIT contracts are the fixed price, the fixed premium, and the minimum price guarantee. The model allows the identification of the optimal time to deploy a renewable energy project and the value of the tariff that maximizes the social we...
Nervous tissue homeostasis requires the regulation of microglia activity. Using conditional gene targeting in mice, we demonstrate that genetic ablation of the small GTPase Rhoa in adult microglia is sufficient to trigger spontaneous microglia activation, producing a neurological phenotype (including synapse and neuron loss, impairment of long-term potentiation [LTP], formation of β-amyloid plaques, and memory ...