50 documents found, page 1 of 5
Adiponectin, Leptin, and IGF-1 Are Useful Diagnostic and Stratification Biomark...
Marques, V; Afonso, MB; Bierig, N; Duarte-Ramos, F; Santos-Laso, Á; Jimenez-Agüero, R; Eizaguirre, E; Bujanda, L; Pareja, MJ; Luís, R; Costa, ABackground: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease where liver biopsy remains the gold standard for diagnosis. Here we aimed to evaluate the role of circulating adiponectin, leptin, and insulin-like growth factor 1 (IGF-1) levels as non-invasive NAFLD biomarkers and assess their correlation with the metabolome. Materials and Methods: Leptin, adiponectin, and IGF-1 seru...
Role of CYP46A1 in brain cholesterol homeostasis
Rodrigues, E; Milagre, I; Nunes, MJ; Gama, MJ; Rodrigues, CMP
Evaluation of the protective role of glutathione S-transferase pi against MPTP ...
Gama, MJ; Carvalho, ANeves; Rodrigues, E; Castro-Caldas, M; Rodrigues, CMP
Molecular and Cell Biology of Eukaryotic Systems
Rodrigues, CMP; Gama, MJ; Moreira da Silva, IB; Rodrigues, E; Solá, S; Castro-Caldas, M; Castro, RE; Ramalho, RM; Nunes, AF; Amaral, JD; Borralho, PM
Plasma levels of ursodeoxycholic acid in black bears, Ursus americanus
Sola, S; Garshelis, DL; Amaral, JD; Noyce, KV; Coy, PL; Steer, CJ; Iaizzo, PA; Rodrigues, CMPTo date, no other studies have examined the seasonal changes in circulating levels of various bile acids in the plasma of wild North American black bears, Ursus americanus. Using gas chromatography, bile acid concentrations were measured in plasma samples
Modulation of Hepatocyte Apoptosis
Solá, S; Amaral, JD; Aranha, MM; Steer, CJ; Rodrigues, CMP
Modulation of cell cycle proteins with a role on apoptosis of primary rat hepat...
Castro, REM; Kren, BT; Steer, CJ; Rodrigues, CMP
Nuclear steroid receptors modulate cellular trafficking of ursodeoxycholic acid...
Sola, S; Amaral, JD; Castro, RE; Ramalho, RM; Kren, BT; Steer, CJ; Rodrigues, CMP
Nuclear translocation of UDCA by the glucocorticoid receptor is required to red...
Sola, S; Amaral, J; Castro, RE; Ramalho, RM; Borralho, PM; Kren, BT; Tanaka, H; Steer, CJ; Rodrigues, CMPUrsodeoxycholic acid (UDCA) inhibits classical mitochondrial pathways of apoptosis by either directly stabiliz* mitochondrial membranes or modulating specific upstream targets. Furthermore, UDCA regulates apoptosis-related genes from transforming growth f
Modulation of neurotoxicity associated with Alzheimer's disease-linked amyloid ...
Ramalho, RM; Borralho, PM; Sola, S; Castro, RE; Amaral, JD; Rodrigues, CMP