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Open science and ethics: issues and dilemmas

Rodrigues, Diana; Lopes, Mafalda; Coelho, Patrícia; Silva, Rosa; Rodrigues, Diana; Lopes , Mafalda; Coelho, Patrícia; Silva, Rosa

Open Science (OS) is a set of principles and practices that aims to make all areas of scientific research accessible, bringing benefits to both researchers and society. In a health context, OS can accelerate the dissemination and disclosure of research results, offering advantages for researchers, health professionals, and society. This short communication aims to analyze the contribution of OS to the dissemina...


Novel recombinant Human Serum Albumin-SPE systems for ochratoxin A determinatio...

Rodrigues, Diana; Aguiar, Tatiana Quinta; Domingues, Lucília; Abrunhosa, Luís

Ochratoxin A (OTA) is a mycotoxin that raises food safety concerns in several products, requiring analytical control. Aiming to develop an alternative to immunoaffinity columns (IACs) for OTA extraction and clean-up, recombinant human serum albumin (rHSA) was explored as an affinity bioreceptor for solid-phase extraction (SPE) applications. rHSA was obtained from Pichia pastoris fused with a C-terminal His6 tag...


Needs of family caregivers of the person with lower limb amputation: scoping re...

Rodrigues, Diana; Castanheira, Sofia; Carvalho, António Luís; Barroso, Cristina

Introduction: Lower limb amputation has a great physical impact, with functional limitations and increased dependence on daily living activities that generate changes in the quality of life of the amputee and family. Support and care to the amputee are provided by the family caregiver, who experiences multiple feelings and needs in the transition to their new role. Identification of these needs is fundamental t...



Exploring consumer behavior and brand management in the automotive sector: insi...

Rodrigues, Diana; Sousa, Bruno; Oliveira, José; Lopes, Eunice; Gomes, Sofia

Human beings are strongly influenced by their emotions; so, it is believed that building a close relationship between consumers and brands is a key factor for success. In this way, car brands are no exception, and despite facing numerous challenges associated with the energy transition, they have to reinvent themselves, retaining a focus on offering a unique and personalized experience for the consumer without ...


Chronic treatment with D2-antagonist haloperidol leads to inhibitory/excitatory...

Santa, Cátia; Rodrigues, Diana; Coelho, Joana F.; Anjo, Sandra I.; Mendes, Vera M.; Bessa-Neto, Diogo; Dunn, Michael J.; Cotter, David; Baltazar, Graça

Striatal dysfunction has been implicated in the pathophysiology of schizophrenia, a disorder characterized by positive symptoms such as hallucinations and delusions. Haloperidol is a typical antipsychotic medication used in the treatment of schizophrenia that is known to antagonize dopamine D2 receptors, which are abundantly expressed in the striatum. However, haloperidol's delayed therapeutic effect also sugge...


Needs of family caregivers of the person with lower limb amputation: scoping re...

Rodrigues, Diana; Castanheira, Sofia; Carvalho, Luís; Barroso, Cristina

Introduction: Lower limb amputation has a great physical impact, with functional limitations and increased dependence on daily living activities that generate changes in the quality of life of the amputee and family. Support and care to the amputee are provided by the family caregiver, who experiences multiple feelings and needs in the transition to their new role. Identification of these needs is fundamental t...

Date: 2023   |   Origin: Millenium

Exploring Consumer Behavior and Brand Management in the Automotive Sector: Insi...

Rodrigues, Diana; Sousa, Bruno; Gomes, Sofia; Oliveira, José; Lopes, Eunice

Human beings are strongly influenced by their emotions; so, it is believed that building a close relationship between consumers and brands is a key factor for success. In this way, car brands are no exception, and despite facing numerous challenges associated with the energy transition, they have to reinvent themselves, retaining a focus on offering a unique and personalized experience for the consumer without ...

Date: 2023   |   Origin: CiencIPCA

PO 116 - THIRTY-DAY MORBIMORTALITY OF PATIENTS ADMITTED IN AN ACADEMIC MEDICAL ...

´Rouxinol Dias, Ana Lídia; Rodrigues, Diana; Ferreira, Leonardo; Lima, Ana Patrícia; Ramos, Patrícia; Santos, Alice

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Are frail patients more susceptible to intraoperative hypotension and 30-day mo...

Fonseca, Diana; Gomes, Fátima; Barros, Marisa; Rouxinol-Dias, Ana Lídia; Fernandes, Mariana; Machado, Andreia; Rodrigues, Diana; Lusquinhos, João

Introduction: Frailty has been considered to be an important predictor of surgical morbimortality, influencing both short and long-term postoperative mortality. Despite this association, less is known about frailty's impact in intraoperative hemodynamic stability, namely intraoperative hypotension, which may influence postoperative outcomes. We aimed to evaluate if frail patients submitted to elective surgery a...


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