8 documents found, page 1 of 1
Microvascular, biochemical, and clinical impact of hyperbaric oxygen therapy in...
Martins-Mendes, Daniela; Costa, Raquel; Rodrigues, Ilda; Camacho, Óscar; Coelho, Pedro Barata; Paixão-Dias, Vítor; Luís, Carla; Pereira, Ana CláudiaBackground: Diabetic foot ulcers (DFUs) are a serious complication of diabetes and are often difficult to treat. Hyperbaric oxygen therapy (HBOT) has been proposed as an adjunctive treatment to promote healing, but its long-term clinical and biological effects remain insufficiently characterized. This study aimed to evaluate the impact of HBOT on systemic biomarkers, local microvasculature, and clinical outcome...
Hóteis Pestana - Atos de fala e outros mecanismos de persuasão: análise de 50 p...
Rodrigues, IldaEste trabalho, inscrito no âmbito da Pragmática, tem como principal foco a análise de posts publicados na página de Facebook da cadeia de hotéis “Pestana”, com o objetivo de perceber quais os atos ilocutórios mais frequentes e verificar os mecanismos mais utilizados para intensificar a sua força ilocutória. A partir do corpus selecionado, as tarefas realizadas foram as seguintes: i) identificação do tipo de des...
Decellularized small intestine for burn wound treatment: a tissue engineering p...
Silva, Inês V.; Rosadas, Marta; Rodrigues, Ilda; Sousa, Clara; Ribeiro, Viviana; Costa, Raquel; Moroni, Lorenzo; Oliveira, Ana L.Introduction: Burn injuries are a significant global health issue, causing approximately 11 million injuries and 180,000 fatalities each year (1). Beyond physical trauma, burn injuries lead to complications such as infections and sepsis. Burn scars can also diminish quality of life by affecting joint mobility and daily activities (2,3). Conventional dressings and autografts have limitations, necessitating novel...
Exploring silk Sericin for diabetic wounds: an in situ-forming hydrogel to prot...
Baptista-Silva, Sara; Bernardes, Beatriz G.; Borges, Sandra; Rodrigues, Ilda; Fernandes, Rui; Gomes-Guerreiro, Susana; Pinto, Marta TeixeiraChronic wounds are one of the most frequent complications that are associated with diabetes mellitus. The overproduction of reactive oxygen species (ROS) is a key factor in the delayed healing of a chronic wound. In the present work, we develop a novel in situ-forming silk sericin-based hydrogel (SSH) that is produced by a simple methodology using horseradish peroxidase (HRP) crosslinking as an advanced dressin...
Establishing a Link between Endothelial Cell Metabolism and Vascular Behaviour ...
Silva, Carolina; Sampaio-Pinto, Vasco; Andrade, Sara; Rodrigues, Ilda; Costa, Raquel; Guerreiro, Susana; Carvalho, Eugenia; Pinto-do-Ó, PerpétuaVascular complications contribute significantly to the extensive morbidity and mortality rates observed in people with diabetes. Despite well known that the diabetic kidney and heart exhibit imbalanced angiogenesis, the mechanisms implicated in this angiogenic paradox remain unknown. In this study, we examined the angiogenic and metabolic gene expression profile (GEP) of endothelial cells (ECs) isolated from a ...
Xanthohumol and 8-prenylnaringenin reduce type 2 diabetes–associated oxidative ...
Luís, Carla; Costa, Raquel; Rodrigues, Ilda; Castela, Ângela; Coelho, Pedro; Guerreiro, Susana; Gomes, Joana; Reis, Celso; Soares, RaquelGalectin-3 (Gal3) expression is associated with accumulation of Advanced Glycation End products (AGE), a common feature in diabetes mellitus (DM). The role of Gal3 in oxidative stress is, however, controversial, being considered in the literature to play either a protective role or exacerbating disease. :Herein, we examined the interplay between Gal3 and oxidative stress in a high-fat diet -induced type 2 DMC57...
Higher education methodologies: from urban planning to mathematical issues
Virtudes, Ana L.; Rodrigues, Ilda; Simões, A. M.; Serôdio, RogérioThis article will be focused on higher education learning and teaching methodologies, based on the experience of the Master Degree in Civil Engineering at the University of Beira Interior, in Covilhã (Portugal). It aims to present the results of the practises used by scholar of urban planning and mathematical issues, both regarding the civil engineering research field. Actually, there are some similarities in b...
Vasculogenesis and Diabetic Erectile Dysfunction: How Relevant Is Glycemic Cont...
Castela, Angela; Gomes, Pedro; Silvestre, Ricardo Jorge Leal; Guardão, Luísa; Leite, Liliana; Chilro, Rui; Rodrigues, Ilda; Vendeira, PedroErectile dysfunction (ED) is a complication of diabetes, condition responsible for causing endothelial dysfunction (EDys) and hampering repair mechanisms. However, scarce information is available linking vasculogenesis mediated by Endothelial Progenitor Cells (EPCs) and diabetes-associated ED. Furthermore, it remains to be elucidated if glycemic control plays a role on EPCs functions, EPCs modulators, and penil...