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Effects of a Mikania laevigata extract on bone resorption and RANKL expression ...

Benatti, B. B.; Campos-Júnior, Jozafá C.; Silva-Filho, Vilmar J.; Alves, Polyanna Miranda; Rodrigues, Isabela R.; Uber-Bucek, Elizabeth

Objectives: The Mikania laevigata extract (MLE) (popularly known in Brazil as "guaco") possesses anti-inflammatory properties. In the present study we tested the effects of MLE in a periodontitis experimental model in rats. We also investigated possible mechanisms underlying such effects. Material and Methods: Periodontal disease was induced by a ligature placed around the mandibular first molars of each animal...

Date: 2020   |   Origin: Oasisbr
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