4 documents found, page 1 of 1
The contribution of second primary cancers to the mortality of patients with a ...
Gonçalves, E; Fontes, F; Rodrigues, JR; Calisto, R; Bento, MJ; Lunet, N; Morais, SPurpose: Second primary cancers (SPCs) are estimated to affect nearly 5% of patients with breast cancer within 10 years of their diagnosis. This study aimed to estimate the contribution of SPCs to the mortality of patients with a breast first primary cancer (FPC). Methods: A population-based cohort of 17,210 patients with a breast FPC diagnosed between 2000 and 2010 was followed for SPCs (31/12/2015) and vital ...
Second primary cancers among females with a first primary breast cancer: a popu...
Gonçalves, E; Fontes, F; Rodrigues, JR; Calisto, R; Bento, MJ; Lunet, N; Morais, S"Purpose To estimate the incidence rate of second primary cancers (SPCs) and the cumulative incidence of metachronous [diagnosed > 2 months after a first primary cancer (FPC)] SPCs in patients with a breast FPC, and to compare the incidence of SPC [overall, synchronous (≤ 2 months of the FPC) and metachronous] with that expected in the general female population. Methods A cohort of patients with a breast FPC fr...
Clinical evaluation of proximal contacts of Class II esthetic direct restorations
Prakki, A.; Cilli, R.; Saad, JOC; Rodrigues, JRMade available in DSpace on 2020-12-10T16:32:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2004-11-01; Objective: This study evaluated the effectiveness of proximal contacts in Class II restorations using two types of matrix bands (steel and polyester) with two different restoration techniques (incremental and with prepolymerized particles). Method and materials: Eighty-eight Class II adjacent restoratio...
Hydrolysis of the phosphoanhydride linkage of cyclic ADP-ribose by the Mn2+-dep...
Canales, J; Fernández, A; Rodrigues, JR; Ferreira, R; Meireles Ribeiro, J; Cabezas, A; Costas, MJ; Cameselle, JCCyclic ADP-ribose (cADPR) metabolism in mammals is catalyzed by NAD glycohydrolases (NADases) that, besides forming ADP-ribose, form and hydrolyze the N1-glycosidic linkage of cADPR. Thus far, no cADPR phosphohydrolase was known. We tested rat ADP-ribose/CDP-alcohol pyrophosphatase (ADPRibase-Mn) and found that cADPR is an ADPRibase-Mn ligand and substrate. ADPRibase-Mn activity on cADPR was 65-fold less effici...