5 documents found, page 1 of 1
Impact of a legumes diet on the human gut microbiome articulated with fecal and...
Ferreira, Helena; Duarte, Daniela; Carneiro, Tatiana J.; Costa, Célia; Barbosa, Joana C.; Rodrigues, João E.; Alves, Paulo; Vasconcelos, MartaBackground & aims: Legumes intake is known to be associated with several health benefits the origins of which is still a matter of debate. This paper addresses a pilot small cohort to probe for metabolic aspects of the interplay between legumes intake, human metabolism and gut microbiota. Methods: Untargeted nuclear magnetic resonance (NMR) metabolomics of blood plasma and fecal extracts was carried out, in tan...
Systematic Review and Meta-Analysis of Mass Spectrometry Proteomics Applied to ...
Rodrigues, João E.; Martinho, Ana; Santa, Cátia; Madeira, Nuno; Coroa, Manuel; Santos, Vítor; Martins, Maria J.; Pato, Carlos N.; Macedo, AntónioMass spectrometry (MS)-based techniques can be a powerful tool to identify neuropsychiatric disorder biomarkers, improving prediction and diagnosis ability. Here, we evaluate the efficacy of MS proteomics applied to human peripheral fluids of schizophrenia (SCZ) patients to identify disease biomarkers and relevant networks of biological pathways. Following PRISMA guidelines, a search was performed for studies t...
The SOUL family of heme-binding proteins: structure and function 15 years later
Goodfellow, Brian J.; Freire, Filipe; Carvalho, Ana Luísa; Aveiro, Susana S.; Charbonnier, Peggy; Moulis, Jean-Marc; Delgado, LeonildoThe SOUL, or heme-binding protein HBP/SOUL, family represents a group of evolutionary conserved putative heme-binding proteins that contains a number of members in animal, plant and bacterial species. The structures of the murine form of HEBP1, or p22HBP, and the human form of HEBP2, or SOUL, have been determined in 2006 and 2011 respectively. In this work we discuss the structures of HEBP1 and HEBP2 in light o...
Assessment of water quality parameters and their seasonal behaviour in a Portug...
Chaves, Raquel S.; Salvador, Daniel; Nogueira, Paulo Jorge; Santos, Miguel M.; Aprisco, Paula; Neto, Célia; Cardoso, Vítor; Benoliel, Maria J.Water quality monitoring is a fundamental tool in the management of freshwater resources. The purpose of monitoring is to provide meaningful quality data for local action planning and catchment-wide decision making. The assessment of water quality is crucial to guarantee the efficient operation of the Water Treatment Plants (WTPs), promoting health conditions and contributing for a more sustainable urban water ...
The SOUL family of heme-binding proteins: structure and function 15 years later
Goodfellow, Brian J.; Freire, Filipe; Carvalho, Ana Luísa; Aveiro, Susana; Charbonnier, Peggy; Moulis, Jean-Marc; Delgado, Leonildo; Ferreira, Gloria C.The SOUL, or heme-binding protein HBP/SOUL, family represents a group of evolutionary conserved putative heme-binding proteins that contains a number of members in animal, plant and bacterial species. The structures of the murine form of HEBP1, or p22HBP, and the human form of HEBP2, or SOUL, have been determined in 2006 and 2011 respectively. In this work we discuss the structures of HEBP1 and HEBP2 in light o...