9 documents found, page 1 of 1

Modeling TEWL-desorption curves

The objective of the present study was to test the discriminative capacity of the mathematical modeling of the transepidermal water loss (TEWL) curves that result from a plastic occlusion stress test (POST) to variations in the skin barrier - insults inflicted to the skin or differences in two distinct anatomical regions. This study was exclusively performed in the arm. On the first part of the work, three diff...

Influence of the time of occlusion on the quantitative parameters obtained by m...

Understanding the human cutaneous barrier function is one of the main goals in the study of skin physiology. The plastic occlusion stress test (POST) is a well-known, dynamic approach for studying the barrier, evoking an over-stimulation of the cutaneous water assessed by the trans-epidermal water loss (TEWL) measurement. Rigorous data analysis is imperative, and the compartmental model proposed is particularly...

Exploring the influence of skin perfusion on transepidermal water loss

Background: Eventual relationships between the vascular function and transepidermal water loss (TEWL), in vivo, have not been entirely explored. By promoting local perfusion alterations through a well-known challenge test, the 'tourniquet-cuff occlusion' manoeuvre, the present study searches for other dynamical factors influencing the cutaneous barrier, further exploring the applicability of these flow-related ...

Assessment of the performance of a new generation of tewameters

Development of a new methodology to assess cutaneous hydration

Photodamage induced by UV radiation on the skin

In vivo evaluation of photoprotective activity of solid lipid nanoparticles for...

Quantification of skin barrier recovery by compartmental modelling of TEWL in b...

Quantitative description of human skin water dynamics by a disposition-decompos...

Background: In vivo water assessment would greatly benefit from a dynamical approach since the evaluation of common related variables such as trans -epidermal water loss or "capacitance" measurements is always limited to instantaneous data. Mathematical modelling is still an attractive alternative already attempted with bi-exponential empirical models. A classical two-compartment interpretation of such models r...