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Assessment of calcinosis in Portuguese patients with systemic sclerosis: a mult...

Samões, Beatriz; Guimarães da Fonseca, Diogo; Beirão, Tiago; Costa, Flávio; Vieira, Romana; Terroso, Georgina; Ferreira, Raquel Miriam; Nicolau, Rafaela

Introduction/objectives: The study aims to define the clinical and subclinical calcinosis prevalence, the sensitivity of radiographed site and clinical method for its diagnosis, and the phenotype of Portuguese systemic sclerosis (SSc) patients with calcinosis. Method: A cross-sectional multicenter study was conducted with SSc patients fulfilling Leroy/Medsger 2001 or ACR/EULAR 2013 classification criteria, regi...


Predictors of cardiac involvement in idiopathic inflammatory myopathies

Bandeira, Matilde; Dourado, Eduardo; Melo, Ana Teresa; Martins, Patrícia; Fraga, Vanessa; Ferraro, José Luís; Saraiva, André; Sousa, Marlene

Objectives: Idiopathic inflammatory myopathies (IIM) are a group of rare disorders that can affect the heart. This work aimed to find predictors of cardiac involvement in IIM. Methods: Multicenter, open cohort study, including patients registered in the IIM module of the Rheumatic Diseases Portuguese Register (Reuma.pt/Myositis) until January 2022. Patients without cardiac involvement information were excluded....


Reuma.pt/vasculitis : the Portuguese vasculitis registry

Ponte, Cristina; Khmelinskii, Nikita; Teixeira, Vítor; Luz, Karine; Peixoto, Daniela; Rodrigues, Marília; Luís, Mariana; Teixeira, Lídia; Sousa, Sandra

Background: The vasculitides are a group of rare diseases with different manifestations and outcomes. New therapeutic options have led to the need for long-term registries. The Rheumatic Diseases Portuguese Register, Reuma.pt, is a web-based electronic clinical record, created in 2008, which currently includes specific modules for 12 diseases and > 20,000 patients registered from 79 rheumatology centres. On Oct...


Management of infections in rheumatic patients receiving biological therapies. ...

Teixeira, Lídia; Fonseca, Ana Rita; Eugénio, Gisela; Rodrigues, Marília; Khmelinskii, Nikita; Fernandes, Sílvia; Serra, Sofia; Costa, Tiago

Introduction: Infections are a major cause of morbidity and mortality in systemic inflammatory rheumatic diseases and the management of infectious complications in patients under biological therapies deserves particular attention. Objective: Develop evidence-based recommendations for the management of infections in rheumatic patients receiving biological therapies. Methods: A search in PubMed (until 10 November...


Desenvolvimento de um modelo computacional do balanço social sistêmico dinâmico

Rodrigues, Marília

Submitted by Maicon Juliano Schmidt (maicons) on 2015-05-05T13:21:40Z No. of bitstreams: 1 Marília Rodrigues.pdf: 4635899 bytes, checksum: e6ae4c9abe358047ed6135bcdbcb3480 (MD5); Made available in DSpace on 2015-05-05T13:21:40Z (GMT). No. of bitstreams: 1 Marília Rodrigues.pdf: 4635899 bytes, checksum: e6ae4c9abe358047ed6135bcdbcb3480 (MD5) Previous issue date: 2014-02-27; CAPES - Coordenação de Aperfeiçoamento...

Date: 2015   |   Origin: Oasisbr

DIAGNOSIS AND MANAGEMENT OF COWS’ MILK PROTEIN ALLERGY IN INFANTS AND CHILDREN

Salvador, Marlene; Rodrigues, Marília; Cordeiro, Ana; Paiva Lopes, Maria João

Cow’s milk protein allergy is an increasingly prevalent and more prolonged disease. Cow’s milk protein allergy is the most common food allergy in infants with a prevalence of approximately 2% to 3%. It may develop even in exclusively breastfed infants. It can manifest through a wide variety of symptoms depending on whether the type of immune response is IgE or non-IgE mediated. Symptoms and signs related to cow...


Anthocyanins restore behavioral and biochemical changes caused by streptozotoci...

Gutierres, Jessié M.; Carvalho, Fabiano B.; Schetinger, Maria Rosa C.; Marisco, Patrícia; Agostinho, Paula; Rodrigues, Marília; Rubin, Maribel A.

Aims The aim of this study was to analyze if the pre-administration of anthocyanin on memory and anxiety prevented the effects caused by intracerebroventricular streptozotocin (icv-STZ) administration-induced sporadic dementia of Alzheimer's type (SDAT) in rats. Moreover, we evaluated whether the levels of nitrite/nitrate (NOx), Na+,K+-ATPase, Ca2 +-ATPase and acethylcholinesterase (AChE) activities in the cere...


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