20 documents found, page 1 of 2
Oregano essential oil: an effective and non-toxic approach for prevent or treat...
Fernandes, Liliana Sousa; Silva, Inês; Blázquez, Elena; Tejada, Ainara; Ribeiro, Artur; Silva, Sónia Carina; Mira, Nuno; Cussó, LorenaVulvovaginal candidiasis (VVC) is one of the most prevalent vaginal infectious diseases, and the emergence of drug-resistant Candida strains has presented a growing challenge in its treatment. This highlights the urgent need to develop effective and non-toxic alternative treatments. In this context, essential oils (EOs) have emerged as a promising alternative considering low toxicity and high antimicrobial acti...
Effect of phage vB_EcoM_FJ1 on the reduction of ETEC O9:H9 infection in a neona...
Ferreira, Alice Maria Fernandes; Silva, Daniela; Almeida, Carina; Rodrigues, Maria Elisa Costa; Silva, Sónia Carina; Castro, Joana Isabel ReisEnterotoxigenic Escherichia coli (ETEC) colonizes the intestine of young pigs causing severe diarrhoea and consequently bringing high production costs. The rise of antibiotic selective pressure together with ongoing limitations on their use, demands new strategies to tackle this pathology. The pertinence of using bacteriophages as an alternative is being explored, and in this work, the efficacy of phage vB\_Eco...
Vapor-phase of essential oils as a promising solution to prevent Candida vagina...
Fernandes, Liliana Sousa; Gonçalves, Bruna Fernandes; Costa, Raquel; Fernandes, Ângela; Gomes, Ana; Nogueira-Silva, Cristina; Silva, Sónia CarinaBackground: Vulvovaginal candidiasis (VVC) is a disease with high incidence, a huge impact on the quality of life and health of women, and which represents a great challenge to treat. The growing need to apply antifungal intensive therapies have contributed to an emergence of drug-resistant Candida strains. Thus, effective therapeutic options, to meet the antifungal-resistance challenge and to control high resi...
Anti-biofilm formulations, and uses thereof
Vaz, Irene Graça Azevedo Pina; Lopes, Maria Ascensão; Ferreira, Inês Ribeiro Valente Lucas; Henriques, Mariana; Rodrigues, Maria Elisa CostaPublication Number WO/2022/090568; An anti-biofilm formulation for use in the treatment of infections comprising: methyl ethyl ketone and an organic co-solvent or an essential oil, wherein the anti-biofilm formulation is a biofilm disruptor.; info:eu-repo/semantics/publishedVersion
Essential oils as a good weapon against drug-resistant Candida auris
Fernandes, Liliana Sousa; Ribeiro, Rita; Costa, Raquel; Henriques, Mariana; Rodrigues, Maria Elisa CostaCandida auris is a recently found Candida species, mainly associated with nosocomial outbreaks in intensive care hospital settings, and unlike other Candida species, it can be transmitted through person-to-person or by contact with surfaces. C. auris is described as resistant to first-line antifungals and, consequently, associated with high mortality. Nowadays, essential oils (EOs) are known to be effective aga...
Portuguese honeys as antimicrobial agents against Candida species
Fernandes, Liliana Sousa; Ribeiro, Henrique Gonçalves; Oliveira, Ana C. A.; Silva, Ana Sanches; Freitas, Andreia; Henriques, MarianaBackground and aim Honey has been recognized worldwide for its antioxidant, anti-tumor, anti-inflammatory and antimicrobial properties. Among them, the antifungal properties associated to honey make it an attractive alternative treatment for Candida-associated infections, particularly for topical application to the mucous membranes and skin. In this sense, the main purpose of this work was to evaluate physicoch...
Honey as a strategy to fight Candida tropicalis in mixed-biofilms with Pseudomo...
Fernandes, L.; Oliveira, A.; Henriques, Mariana; Rodrigues, Maria Elisa CostaFungal contaminations with Candida species are commonly responsible for several infections, especially when associated to bacteria. The therapeutic approach commonly used is being compromised due to microbial resistances of these microorganisms to antimicrobial agents, especially in biofilm. The use of honey as an antimicrobial agent has been emerging as a valuable solution and proving its potential in plankton...
Advances in Candida sp. Biofilm Mannans
Romo, Jesus A.; Rodrigues, Maria Elisa Costa; Fernandes, Liliana Sousa; Papp, Csaba; Gácser, Attila; Rodrigues, Célia FortunaCandida species belong to the normal human microbiota and are commonly responsible for several clinical manifestations from mucocutaneous overgrowth to severe bloodstream infections. Candida albicans is the predominant species involved in disease conditions. Nevertheless, in the last decade, the number of infections due to non-albicans Candida (NAC) species has significantly increased. Candida species have seve...
Pseudomonas aeruginosa-Candida albicans polymicrobial biofilms in ventilator-as...
Grainha, Tânia; Lopes, Susana Patrícia; Rodrigues, Maria Elisa Costa; Magalhães, Andreia Patrícia Alves; Pereira, Maria OlíviaIntroduction: Mixed bacterial-fungal colonization of the endotracheal tubes is now evident, with microbial interplay withstanding common antimicrobial therapy and paying for persistent and severe VAP infections. While alternative therapeutic strategies effectively targeting inter-kingdom biofilms are required, the role of each microorganism need to be appraised to deliver effective treatments. Hypothesis and ai...
Plant phenolic extracts as an effective strategy to control Staphylococcus aure...
Gomes, Fernanda Isabel; Martins, Natália; Barros, Lillian; Rodrigues, Maria Elisa Costa; Oliveira, Maria Beatriz; Henriques, MarianaStaphylococcus aureus is one of the most common contagious mastitis pathogens. Bovine mastitis is considered an important reservoir for dairy industry contamination, and therefore to ensure S. aureus control has gained a pivotal importance. Natural matrices present multiple biological effects, being its antimicrobial potential increasingly reported. Thus, the present study aims to assess the antibacterial activ...