26 documents found, page 1 of 3
Vapor phase of white thyme essential oil: effect on Candida albicans and preser...
Fernandes, Liliana Sousa; Silva, Inês da; Araújo, Daniela Eira; Costa, Raquel Pinho; Silva, Sónia Carina; Mira, Nuno Pereira; Costa-de-Oliveira, SofiaThe balance of the vaginal ecosystem results from synergistic interactions established between the different colonizing microorganisms. Lactobacillus spp. stands out as a predominant member, acting a crucial protective role in maintaining vaginal health. As vulvovaginal candidiasis remains prevalent and antifungal resistance grows, there is a pressing need for alternative therapies. However, any development of ...
Chemical composition, biocompatibility, and anti-Candida albicans activity of S...
Andrade, João; Almeida-Apolonio, Adriana; Dantas, Fabiana; Nogueira, Cláudio; Pinto, Luciano; Moraes, Carlos; Fernandes, Liliana SousaRecurrent vulvovaginal candidiasis (RVVC), predominantly caused by Candida albicans, represents a global health issue, particularly in developing regions. This study explores the antifungal potential of aqueous leaf extract of Schinus weinmanniifolia Mart. ex Engl., a native Latin American plant. The extract was evaluated for phytochemical composition, antifungal efficacy, and safety profile. Phytochemical anal...
Development and evaluation of microencapsulated oregano essential oil as an alt...
Fernandes, Liliana Sousa; Barco-Tejada, Ainara; Blázquez, Elena; Araújo, Daniela Eira; Ribeiro, Artur; Silva, Sónia Carina; Cussó, LorenaVulvovaginal candidiasis (VVC) is characterized as a very common fungal infection that significantly affects womens health worldwide. Essential oils (EOs) are currently being evaluated as an alternative therapy. The development of efficient techniques such as micro- or nanoencapsulation for protecting and controlling release is essential to overcome the limitations of EO applications. Therefore, the aim of this...
Glycyrrhiza glabra hydroethanolic extract and manuka honey alone and in combina...
Gomes, Fernanda Isabel Antunes; Dias, Maria Inês; Rodrigues, Maria Elisa Costa; Barros, Lillian; Henriques, MarianaBackground The natural tendency of polymicrobial infections and co-habitation of bacteria and Candida are currently well-recognized and reported as highly fatal. This kind of interaction is usually associated with drug tolerance, infection relapse, persistence and high mortality. The interest in natural products has emerged and their potential applicability as therapeutic strategies is being constantly explored...
Oregano essential oil: an effective and non-toxic approach for prevent or treat...
Fernandes, Liliana Sousa; Silva, Inês; Blázquez, Elena; Tejada, Ainara; Ribeiro, Artur; Silva, Sónia Carina; Mira, Nuno; Cussó, LorenaVulvovaginal candidiasis (VVC) is one of the most prevalent vaginal infectious diseases, and the emergence of drug-resistant Candida strains has presented a growing challenge in its treatment. This highlights the urgent need to develop effective and non-toxic alternative treatments. In this context, essential oils (EOs) have emerged as a promising alternative considering low toxicity and high antimicrobial acti...
Effect of phage vB_EcoM_FJ1 on the reduction of ETEC O9:H9 infection in a neona...
Ferreira, Alice Maria Fernandes; Silva, Daniela; Almeida, Carina; Rodrigues, Maria Elisa Costa; Silva, Sónia Carina; Castro, Joana Isabel ReisEnterotoxigenic Escherichia coli (ETEC) colonizes the intestine of young pigs causing severe diarrhoea and consequently bringing high production costs. The rise of antibiotic selective pressure together with ongoing limitations on their use, demands new strategies to tackle this pathology. The pertinence of using bacteriophages as an alternative is being explored, and in this work, the efficacy of phage vB\_Eco...
Anti-biofilm formulations, and uses thereof
Vaz, Irene Graça Azevedo Pina; Lopes, Maria Ascensão; Ferreira, Inês Ribeiro Valente Lucas; Henriques, Mariana; Rodrigues, Maria Elisa CostaAn anti-biofilm formulation for use in the treatment of infections comprising: methyl ethyl ketone and an organic co-solvent or an essential oil, wherein the anti-biofilm formulation is a biofilm disruptor.
Efeito da fase de vapor de óleos essenciais em Candida albicans e Lactobacillus...
Fernandes, Liliana Sousa; Costa, Raquel; Silva, Sónia Carina; Henriques, Mariana; Rodrigues, Maria Elisa CostaO equilíbrio do ecossistema vaginal é resultado de interações sinérgicas e complexas entre o hospedeiro e os diferentes microrganismos que colonizam a mucosa vaginal. Uma microbiota vaginal saudável é predominantemente constituída por Lactobacillus spp., que desempenham um papel protetor fundamental na prevenção de doenças ginecológicas, como a Candidíase Vulvovaginal (CVV). A CVV é uma infeção comum, causada p...
Vapor-phase of essential oils as a promising solution to prevent Candida vagina...
Fernandes, Liliana Sousa; Gonçalves, Bruna Fernandes; Costa, Raquel; Fernandes, Ângela; Gomes, Ana; Nogueira-Silva, Cristina; Silva, Sónia CarinaBackground: Vulvovaginal candidiasis (VVC) is a disease with high incidence, a huge impact on the quality of life and health of women, and which represents a great challenge to treat. The growing need to apply antifungal intensive therapies have contributed to an emergence of drug-resistant Candida strains. Thus, effective therapeutic options, to meet the antifungal-resistance challenge and to control high resi...
Essential oils as a good weapon against drug-resistant Candida auris
Fernandes, Liliana Sousa; Ribeiro, Rita; Costa, Raquel; Henriques, Mariana; Rodrigues, Maria Elisa CostaCandida auris is a recently found Candida species, mainly associated with nosocomial outbreaks in intensive care hospital settings, and unlike other Candida species, it can be transmitted through person-to-person or by contact with surfaces. C. auris is described as resistant to first-line antifungals and, consequently, associated with high mortality. Nowadays, essential oils (EOs) are known to be effective aga...