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Profiling Persistent Asthma Phenotypes in Adolescents: A Longitudinal Diagnosti...

Amaral, R; Jácome, C; Almeida, R; Pereira, AM; Alves-Correia, M; Mendes, S; Rodrigues, JC; Carvalho, J; Araújo, L; Costa, A; Silva, A; Teixeira, MF

We aimed to identify persistent asthma phenotypes among adolescents and to evaluate longitudinally asthma-related outcomes across phenotypes. Adolescents (13-17 years) from the prospective, observational, and multicenter INSPIRERS studies, conducted in Portugal and Spain, were included (n = 162). Latent class analysis was applied to demographic, environmental, and clinical variables, collected at a baseline med...


Potencial anti-inflamatory effects of artemisia gorgonum on rat liver injury in...

Rodrigues, N; Almeida, A; Silva, H; Pinto, D; Seca, A; Pereira, ML

[No abstract available]


Propylthiouracil Induced Pulmonary-Renal Syndrome: a Case Report.

Boattini, M; Rodrigues, A; Nascimento, P; Luz, KC; Castelo Branco, S; Rodrigues, N; Cachado, P; Garcia, T

Propylthiouracil (PTU) is known to induce antineutrophil cytoplasmatic antibody (ANCA) seropositivity; however, small vessel vasculitis (SVV) with pulmonary and renal involvement is rare. We present the case of an 81-year-old woman on PTU treatment due to toxic nodular goitre who developed alveolar hemorrhage and rapidly progressive glomerulonephritis. The authors highlight the importance of early recognising d...


Thermal comfort evaluation of an operating room through CFD methodology

Rodrigues, N; Teixeira, S; Alberto Miguel; Oliveira, R; Teixeira, J; João Santos Baptista

Different studies have been evidencing that the surgeon, working with a high metabolic rate, feels uncomfortable after a time. This enforces the study of indoor thermal conditions in health care facilities. The main objective of the present work is the evaluation of the thermal comfort sensation experienced by surgeons and nurses inside a Portuguese orthopaedic surgical room, using the PMV index. Through CFD to...


Acute Bivalvular Left-Sided Methicillin-Resistant Staphylococcus Aureus Endocar...

Póvoas, D; Figueiredo, M; Murinello, A; Damásio, H; Ramos, A; Rodrigues, N; Sousa, J; Carvalho, F; Peres, H; Gomes, P

Infective endocarditis (IE) is now rare in developed countries, but its prevalence is higher in elderly patients with prosthetic valves, diabetes, renal impairment, or heart failure. An increase in health-care associated IE (HCAIE) has been observed due to invasive maneuvers (30% of cases). Methicillin-resistant Staphylococcus aureus (MRSA) and Enterococcus are the most common agents in HCAIE, causing high mort...


Treatment of Hepatitis C Virus Infection in Kidney Transplant Recipients: Case ...

Caeiro, F; Baptista, V; Rodrigues, N; Carvalho, D; Aires, I; Remédio, F; Nolasco, F

Chronic hepatitis C virus (HCV) infection exists in a large proportion of patients undergoing renal transplantation. Nowadays it is not considered to be an absolute contraindication to transplantation; however, it is associated with an increased risk for the patient and accounts for a shorter half-life of the renal allograft. We present three transplant recipients who displayed serious hepatic dysfunction after...


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