42 documents found, page 1 of 5
Automated Image Analysis of Lung Branching Morphogenesis from Microscopic Image...
Rodrigues, Pedro L.; Rodrigues, Nuno F.; Duque, Duarte; Granja, Sara; Vilaça, João L.Background. Regulating mechanisms of branching morphogenesis of fetal lung rat explants have been an essential tool for molecular research. This work presents a new methodology to accurately quantify the epithelial, outer contour, and peripheral airway buds of lung explants during cellular development from microscopic images. Methods. The outer contour was defined using an adaptive and multiscale threshold algo...
A-scan ultrasound system for real-time puncture safety assessment during percut...
Rodrigues, Pedro L.; Rodrigues, Nuno F.; Fonseca, Jaime C.; von Krügerd, M. A.; Pereira, W. C. A.; Vilaça, João L.Background: Kidney stone is a major universal health problem, affecting 10% of the population worldwide. Percutaneous nephrolithotomy is a first-line and established procedure for disintegration and removal of renal stones. Its surgical success depends on the precise needle puncture of renal calyces, which remains the most challenging task for surgeons. This work describes and tests a new ultrasound based syste...
Validation of percutaneous puncture trajectory during renal access using 4D ult...
Rodrigues, Pedro L.; Rodrigues, Nuno F.; Fonseca, Jaime C.; Vilaça, João L.Background: An accurate percutaneous puncture is essential for disintegration and removal of renal stones. Although this procedure has proven to be safe, some organs surrounding the renal target might be accidentally perforated. This work describes a new intraoperative framework where tracked surgical tools are superimposed within 4D ultrasound imaging for security assessment of the percutaneous puncture trajec...
Automated image analysis of lung branching morphogenesis
Rodrigues, Pedro L.; F. Rodrigues, Nuno; Duque, Duarte; Granja, Sara; Correia-Pinto, Jorge; Vilaça, João L.Regulating mechanisms of branchingmorphogenesis of fetal lung rat explants have been an essential tool formolecular research.This work presents a new methodology to accurately quantify the epithelial, outer contour, and peripheral airway buds of lung explants during cellular development frommicroscopic images. Methods.Theouter contour was defined using an adaptive and multiscale threshold algorithm whose level ...
Variations of the soft tissue thicknesses external to the ribs in pectus excava...
Rodrigues, Pedro L.; Direito-Santos, Bruno; Moreira, António H.J.; Fonseca, Jaime C.; Pinho, A.C.M.; F. Rodrigues, Nuno; Henriques-Coelho, TiagoBackground: Surgical repair of pectus excavatum (PE) has become more popular due to improvements in the minimally invasive Nuss procedure. The pre-surgical assessment of PE patients requires Computerized Tomography (CT), as the malformation characteristics vary from patient to patient. Objective: This work aims to characterize soft tissue thickness (STT) external to the ribs among PE patients. It also presents ...
Hand-held robotic device for laparoscopic surgery and training
Pereira, Ricardo; Moreira, António H. J.; Leite, Mariana; Rodrigues, Pedro L.; Queirós, Sandro; F. Rodrigues, Nuno; Leão, Pedro; Vilaça, João L.Laparoscopic surgery (LS) has revolutionized traditional surgical techniques introducing minimally invasive procedures for diagnosis and local therapies. LSs have undeniable advantages, such as small patient incisions, reduced postoperative pain and faster recovery. On the other hand, restricted vision of the anatomical target, difficult handling of the surgical instruments, restricted mobility inside the human...
Application to quantify fetal lung branching on rat explant
Rodrigues, Pedro L.; Granja, Sara; Moreira, António; F. Rodrigues, Nuno; Vilaça, João L.Recently, regulating mechanisms of branching morphogenesis of fetal lung rat explants have been an essential tool for molecular research. The development of accurate and reliable segmentation techniques may be essential to improve research outcomes. This work presents an image processing method to measure the perimeter and area of lung branches on fetal rat explants. The algorithm starts by reducing the noise c...
Automatic modeling of pectus excavatum corrective prosthesis using artificial n...
Rodrigues, Pedro L.; F. Rodrigues, Nuno; Pinho, ACM; Fonseca, Jaime C.; Correia-Pinto, Jorge; Vilaça, João L.Pectus excavatum is the most common deformity of the thorax. Pre-operative diagnosis usually includes Computed Tomography (CT) to successfully employ a thoracic prosthesis for anterior chest wall remodeling. Aiming at the elimination of radiation exposure, this paper presents a novel methodology for the replacement of CT by a 3D laser scanner (radiation-free) for prosthesis modeling. The complete elimination of...
Automatic prebent customized prosthesis for pectus excavatum minimally invasive...
Vilaça, João L.; Rodrigues, Pedro L.; Soares, Tony R.; Fonseca, Jaime; Pinho, ACM; Henriques-Coelho, Tiago; Correia-Pinto, JorgePectus excavatum is the most common deformity of the thorax. A minimally invasive surgical correction is commonly carried out to remodel the anterior chest wall by using an intrathoracic convex prosthesis in the substernal position. The process of prosthesis modeling and bending still remains an area of improvement. The authors developed a new system, i3DExcavatum, which can automatically model and bend the bar...
Assessment of 3D scanners for modeling pectus carinatum corrective bar
Moreira, António H. J.; Fonseca, João Gomes; Rodrigues, Pedro L.; Fonseca, Jaime C.; Pinho, A. C. M.; Correia-Pinto, Jorge; F. Rodrigues, NunoPectus Carinatum (PC) is a chest deformity consisting on the anterior protrusion of the sternum and adjacent costal cartilages. Non-operative corrections, such as the orthotic compression brace, require previous information of the patient chest surface, to improve the overall brace fit. This paper focuses on the validation of the Kinect scanner for the modelling of an orthotic compression brace for the correcti...